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Granola Science https://rvy.ayu.mybluehost.me/ Holistic living, backed by science Fri, 18 Oct 2024 03:55:33 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.3 https://rvy.ayu.mybluehost.me/wp-content/uploads/2023/12/cropped-Granola-Science-32x32.png Granola Science https://rvy.ayu.mybluehost.me/ 32 32 How to Use Vitamin C to Support Your Adrenal Glands (+ DIY Adrenal Cocktail Formula) https://rvy.ayu.mybluehost.me/vitamin-c-adrenal-glands-diy-adrenal-cocktail-formula/?utm_source=rss&utm_medium=rss&utm_campaign=vitamin-c-adrenal-glands-diy-adrenal-cocktail-formula Tue, 05 Mar 2024 22:53:21 +0000 https://rvy.ayu.mybluehost.me/?p=1264 The highest concentration of vitamin C in your whole body is found in your adrenal glands! Vitamin C is used by your adrenal glands to produce cortisol. Because of this, it’s vital to replenish your body’s vitamin C during times of stress when it gets extra depleted. 

Read on to learn how your adrenal glands work, what are signs of adrenal stress, and how to use vitamin C to support your adrenal glands and your stress response system!

The post How to Use Vitamin C to Support Your Adrenal Glands (+ DIY Adrenal Cocktail Formula) appeared first on Granola Science.

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Vitamin C + your adrenal glands = besties. Vitamin C, aka ascorbic acid, plays a critical role in healthy adrenal gland function and production of your stress hormone, cortisol. In fact, the highest concentration of vitamin C in your whole body is found in your adrenal glands! Because of this, it’s especially important to replenish your body’s vitamin C during times of stress when it gets extra depleted. 

Read on to learn how your adrenal glands work, what are signs of adrenal stress, and how to use vitamin C to support your adrenal glands and your stress response system!

What are adrenal glands and what do they do in your body?

Adrenal glands are little pyramid-shaped organs that sit on top of your kidneys like hats. 

They are a key piece of your endocrine system, making a range of critical hormones: cortisol, epinephrine and norepinephrine, aldosterone, and even a little estrogen and testosterone. 

Healthy adrenal gland function is important for several physiological processes in the human body, including:

  • fluid and mineral balance
  • immune system
  • reproductive function
  • metabolism
  • stress response
A diagram showing the adrenal glands on top of the kidneys, with the adrenal hormones explained

Adrenal glands and your body’s stress response system

Adrenal glands are probably best known for their critical role in your body’s stress response system, the hypothalamic-pituitary-adrenal axis  – the HPA axis, for short.

You’ve probably heard of cortisol and epinephrine before. These are *the* stress hormones; the main culprits responsible for the effects of stress. Think: pounding heart, raised blood pressure and heart rate, muscle tension, and increased blood sugar.

Cortisol is made by the adrenal cortex, which is the outer layer of the adrenal gland, while epinephrine is made by the medulla, the inner layer. 

The adrenal glands and their hormones help your body respond quickly to stressful situations – and then return to a normal state quickly as well. (1) (Read more here: How Stress Works (Part 1): Your Body’s Stress Response Pathway + How To Understand It)

What does chronic stress do to adrenal glands?

Stress is a normal physiological response in the human body. When you encounter something your body perceives as threatening, it takes action to keep you safe. These “threats,” or stressors, can be psychological or physical. 

Examples of psychological stressors: stressful working conditions, fighting with a loved one, dealing with traffic, or getting startled

Examples of physical stressors: infection, injury, excessively low or high blood sugar, intense exercise 

Starting in your hypothalamus and then your pituitary gland, hormones and neurotransmitters start a chain reaction to mobilize your body and respond to the stressor.

Stress narrows your focus, spikes blood sugar and blood pressure, and tenses muscles to make you able to react quickly. 

These effects are mediated by cortisol and epinephrine from the adrenal glands. And they are good! …that is, they are good during acute stress. 

But most of us experience chronic stress, which lasts longer than a few hours or a couple days. Chronic stress can last for days, weeks, months, or longer. Prolonged stressful situations means chronically high stress hormones, and that’s when your adrenal health can suffer.

Signs that your adrenal glands are chronically stressed:

  • Low energy
  • Sleep issues: tired in the morning but difficult to fall asleep at night
  • Quick to anger, irritable
  • Dependence on caffeine
  • Poor immune function (get infections easily)
  • Cravings for salty or sweet foods
  • Gut and digestive issues
  • (2)
Infographic listing the signs of adrenal gland stress
A line drawing of a kidney and an adrenal gland on top

What is adrenal fatigue?

While it’s not a clinically recognized disorder, complementary medicine describes adrenal fatigue as an out-of-whack stress response pathway (the HPA axis) resulting in adrenal glands that don’t produce cortisol sufficiently anymore.

The theory goes like this: our modern, hectic lifestyle causes a great deal of stress, making your cortisol levels constantly high. Over time, this chronic stress desensitizes your body to cortisol, causing it to release higher and higher levels, eventually “fatiguing” your adrenal glands when they can’t keep up anymore.  

Adrenal fatigue claims to cause symptoms such as: 

  • Sleep issues
  • Low energy
  • “Brain fog”
  • Low mood 
  • Gut issues
  • (3) 

Since there’s no official diagnostic criteria for adrenal fatigue, mainstream medical doctors might dismiss people who are suffering from these real symptoms. Complementary healthcare providers might delve deeper and offer cortisol testing, but this can be complicated to test as cortisol levels ebb and flow throughout the day. (Read more about Lab tests for stress here).  (4)

What’s the difference between adrenal fatigue and adrenal insufficiency?

Adrenal fatigue is not the same thing as adrenal insufficiency. 

Adrenal insufficiency, also known as Addison’s disease, is when your body doesn’t produce enough adrenal hormones due to autoimmune disease, infection, or tumors affecting your adrenal glands or your pituitary gland. (5) While adrenal fatigue is not recognized by mainstream medicine, it reflects a collection of symptoms that could stem from a chronically activated stress response system.

If not adrenal fatigue, then what are my symptoms cause by?

The symptoms of adrenal fatigue could actually be due to many other health issues, including: 

  • Hormonal impairments, especially high cortisol due to chronic stress
  • Autoimmune diseases
  • Anemia
  • Sleep apnea
  • Depression, anxiety, or other mood disorders
  • (6)

Regardless of the diagnosis for your symptoms, there are simple lifestyle and nutritional approaches you can take to address them in a holistic and functional way. 

(Read more here: 4 steps to optimize the stress response pathway + feel better!)

One great tool to support normal adrenal function is vitamin C – especially if you experience chronic stress. Keep reading for how to use vitamin C for adrenal support.

A photo of sliced lemons, limes, and kiwis

How does vitamin C help the adrenal glands?

Vitamin C acts in several different roles in the body, including the immune system, inflammation, and as an enzyme cofactor.

The highest concentration of vitamin C is found in the adrenal glands. (7). This is because your adrenal glands use vitamin C to synthesize cortisol. So when your body is producing a lot of cortisol, your vitamin C stores get depleted. (8) Other nutrients are needed for the production of cortisol as well, such as the B vitamins niacin and pantothenic acid.

Read on for more specifics on each of these roles

The role of vitamin C in the body

Vitamin C, aka ascorbic acid, is an essential nutrient in your body. That means you can’t synthesize it yourself, so you have to consume it in your diet.

Sufficient vitamin C levels help your body support immunity, fight inflammation, produce collagen, and allow many enzymes to work.

Immunity and inflammatory pathways:

Vitamin C is an antioxidant. That means it can fight oxidative stress in the body; it catches free radicals, neutralizes them, and prevents them from damaging other parts of the cell. (2) Vitamin C is especially protective in the nervous system, which is made of tissues with high amounts of fatty acids that are especially susceptible to oxidative damage. (2)

A line drawing of cellular inflammation, with zig zag lines for inflammation and circle shapes for cells

The ability of vitamin C helps support the immune system, and shorten the duration and severity of colds and other illnesses (9)

Vitamin C supplementation has also been shown to reduce stress, muscle soreness, and pain, which are all most likely due to its role as an antioxidant  (10, 11)

It’s important to note that this is NOT a “more is better” phenomenon. Sufficient levels of vitamin C will help mediate these effects, but a high dose beyond what your body needs will not give you more benefits.

Enzyme cofactor for collagen production:

Vitamin C is an enzyme cofactor to help produce collagen. So proper levels of vitamin C support strong connective tissue and endothelial tissue – think: blood vessels, the lining of your gut, skin, joints, and tendons.

This is also why scurvy, the disease of vitamin C deficiency, results in poor wound healing (one classic sign of scurvy is bloody gums ?) (12)

In addition to helping produce collagen, vitamin C is also an important enzyme cofactor for other processes in the body, including the production of cortisol. See more below for the role of vitamin C in the adrenal glands.

This is also why scurvy, the disease of vitamin C deficiency, results in poor wound healing (one classic sign of scurvy is bloody gums ?) (12)

How does vitamin C work in the adrenal glands?

As mentioned above, the highest concentration of vitamin C in your whole body is found in the adrenal glands. (10) This is because vitamin C is a cofactor for the enzymes that make cortisol. These enzymes are called hydroxylases 

Like the battery for a power drill, these enzymes can’t work properly without vitamin C. And when the enzymes are in high demand (i.e., when you’re stressed out), this “wears out the battery,” using up your stores of vitamin C. (10)

You can help relieve some effects of stress on your body by “recharging your battery,” and consuming adequate vitamin C. Supplying your body with plentiful vitamin C from whole food sources helps soothe the physiological effects of stress. (2)

An image with citrus fruits and leaf greens next to an image of vitamin C supplements

Why choose whole food sources of vitamin C

Studies actually show that your body absorbs natural and synthetic vitamin C the exact same! (12) Ascorbic acid is the same structure whether in a synthetic supplement or a natural whole food source. However! That still doesn’t mean they are equal…

Whole food sources of vitamin C are packaged along with many other beneficial compounds, such as fiber and phytonutrients, while synthetic vitamin C is just ascorbic acid alone. 

In addition, synthetic ascorbic acid is typically processed from corn or wheat, with the purpose of cheap mass industrial production, and not environmental or nutritional benefit (13) 

So you are getting more bang for your buck when you choose whole food sources of vitamin C, from less processed sources. In addition, it’s much easier to overload on excessive amounts of vitamin C in supplement form, which can upset your digestive system (and probably not provide any extra benefit…sorry Linus Pauling). (14)

An infographic with images of kiwis, strawberries, citrus, and other foods that are high in vitamin C

Best sources of whole food vitamin C

The highest sources of vitamin C from whole foods include:

  • Kiwis
  • Strawberries
  • Oranges
  • Red bell peppers
  • Grapefruits
  • Lemons
  • Broccoli
  • Tomatoes
  • (14)

Whole food sources to look for when using vitamin C supplements:

  • Acerola cherries
  • Camu Camu
  • Rose hips

How are trace minerals related to adrenal glands and vitamin C?

Magnesium, potassium, and sodium are three minerals that play a role in adrenal health.

Magnesium can help reduce stress and anxiety by decreasing activation of the HPA axis (15)

Potassium and sodium are two major electrolytes in the body, and these levels are controlled in part by a hormone called aldosterone, which is released from the adrenal gland. 

Since cortisol and aldosterone are both released from the adrenal cortex, and have similar structures, they can bind to each other’s receptors and can have some overlapping effects. For example, when cortisol levels are high, it can cause the kidneys to retain sodium and excrete potassium. This throws off your body’s electrolyte and fluid balance, so it’s important to replenish potassium levels during chronic stress. (16)

Finally, vitamin C is absorbed from the digestive tract through a transport enzyme that requires sodium to function. So sufficient sodium levels are important to be able to absorb vitamin C from your diet! (17)

How to make an adrenal cocktail: whole food vitamin C + trace minerals

An adrenal cocktail is loaded with whole food vitamin C and vital minerals that are thrown off by your adrenal glands during times of stress. This nutritional tool helps maintain proper adrenal function, normal cortisol production, and a healthy stress response system.

Here’s my go-to adrenal cocktail formula:

  • Vitamin C
    • 1/4 to 1/2 cup orange juice or pineapple juice (OR squeeze of half lemon or lime)
  • Potassium
    • 1/4 to 1/2 cup coconut water or aloe vera juice, OR 1/4 cup coconut milk, OR 1/4 teaspoon cream of tartar
  • Sodium
    • Pinch of Sea salt, OR Redmond’s real salt, OR Maldon sea salt flakes
  • Filtered Water
    • 1/4 to 1/2 cup
  • Optional Add-Ins:
    • 1 tablespoon collagen powder
    • 1-2 Tablespoons coconut cream or regular cream
An infographic showing the ingredients needed for an adrenal cocktail recipe, including vitamin C, potassium, and sodium

Summary

Vitamin C is the Robin to your adrenal glands’ Batman – responding to crime, er, stress in the body, making sure you have enough resources to keep your body safe and balanced.

Your adrenal glands are a key part of your body’s stress response system, and they also have the highest concentration of vitamin C in your body. This is because vitamin C is a cofactor for enzymes that make cortisol, your body’s main stress hormone. 

So during times of stress, your vitamin C in your adrenal glands gets depleted. It is helpful to add in vitamin C to your diet to replenish your body’s stores. You can do this with whole food sources of vitamin C, or your own homemade adrenal cocktail.

Let me know in the comments if you’d like more easy recipes and tools to help your body manage stress! Or let me know if you’d like to see a review of some quality vitamin C products and adrenal formulas out there!

References
References
  1. Chrousos, G. P., & Gold, P. W. (1992). The concepts of stress and stress system disorders: overview of physical and behavioral homeostasis. Jama.
  2. Moritz, B., et al. (2020). The role of vitamin C in stress-related disorders. The Journal of Nutritional Biochemistry.
  3. Cook, S. B. (2017). Current Controversy: Does Adrenal Fatigue Exist. Natural Medicine Journal.
  4. Babic, N. et al. (2023). Endocrine testing protocols: hypothalamic pituitary adrenal axis. Endotext.
  5. Alexandraki KI, et al. Adrenal Insufficiency. [Updated 2022 Nov 7]. In: Feingold KR, Anawalt B, Blackman MR, et al., editors. Endotext.
  6. Campos, M. Is adrenal fatigue “real”? Harvard Health Blog. Harvard Medical School
  7. Jenkins, J. S. (1962). The effect of ascorbic acid on adrenal steroid synthesis in vitro. Endocrinology
  8. Padayatty, S. J., et al. (2007). Human adrenal glands secrete vitamin C in response to adrenocorticotrophic hormone. The American journal of clinical nutrition.
  9. Hemilä, H., & Chalker, E. (2023). Vitamin C reduces the severity of common colds: a meta-analysis. BMC Public Health.
  10. Brody, S., et al. (2002). A randomized controlled trial of high dose ascorbic acid for reduction of blood pressure, cortisol, and subjective responses to psychological stress. Psychopharmacology.
  11. Clarkson, P. M., & Thompson, H. S. (2000). Antioxidants: what role do they play in physical activity and health?. The American journal of clinical nutrition.
  12. Carr, A. C., & Vissers, M. C. (2013). Synthetic or food-derived vitamin C—are they equally bioavailable?. Nutrients
  13. Pappenberger, G., & Hohmann, H. P. (2014). Industrial production of L-ascorbic acid (vitamin C) and D-isoascorbic acid. Biotechnology of food and feed additives.
  14. Higdon, J. Vitamin C. [Updated Dec 2018] Linus Pauling Institute. Oregon State University.
  15. Schutten, J. C. et al. (2021). Long‐term magnesium supplementation improves glucocorticoid metabolism: A post‐hoc analysis of an intervention trial. Clinical endocrinology
  16. Fan, L. et al. (2020). Association of hypokalemia with cortisol and ACTH levels in Cushing’s disease. Annals of the New York Academy of Sciences
  17. May, J. M. (2011). The SLC23 family of ascorbate transporters: ensuring that you get and keep your daily dose of vitamin C. British journal of pharmacology.
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An infographic with images of kiwis, strawberries, citrus, and other foods that are high in vitamin C

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Cryotherapy vs Ice Bath: Which Is Better for Your Body? https://rvy.ayu.mybluehost.me/cryotherapy-vs-ice-bath/?utm_source=rss&utm_medium=rss&utm_campaign=cryotherapy-vs-ice-bath https://rvy.ayu.mybluehost.me/cryotherapy-vs-ice-bath/#respond Wed, 28 Feb 2024 17:58:59 +0000 https://rvy.ayu.mybluehost.me/?p=1340 We’ll talk about the key differences between ice baths vs cryotherapy. We’ll cover the health benefits of cold exposure for muscle tissue, the nervous system, and mental health, and the scientific evidence that supports each of these practices, to help you decide whether ice baths vs cryotherapy is best for YOU! I was 10 years...

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We’ll talk about the key differences between ice baths vs cryotherapy. We’ll cover the health benefits of cold exposure for muscle tissue, the nervous system, and mental health, and the scientific evidence that supports each of these practices, to help you decide whether ice baths vs cryotherapy is best for YOU!

Three people sitting in a cold river to use it as an ice bath
Me, my sister-in-law, and my husband doing a cold plunge in a ~55°F river

I was 10 years old when I did my first cold plunge.

(Okay, maybe that wasn’t *exactly* what it was ?)

On a family ski trip, my siblings and I would compete to see who could jump out of the hot tub and lie in the snow for the longest. My younger brother (who I think is part polar bear) always won. 

In recent years, cold exposure – using cryotherapy, ice baths, cold showers, and even ice vests – has become more popular and more intentional. From elite athletes to everyday fitness enthusiasts, people are dunking themselves in icy water or foggy cold chambers, and we’re going to talk about why!

Main Differences Between Ice Baths vs Cryotherapy

How does cryotherapy work?

Cryotherapy is cold exposure using extremely cold air

It’s done in special chambers cooled with liquid nitrogen to get the air temperature between -150°F and -280°F. 

While that temperature might sound intense, cryotherapy doesn’t feel as extreme as icy water to most people. This is because air doesn’t transfer heat very well, so it feels more gradual and less shocking.  

Cryotherapy is short duration, generally for 2-3 minutes. 

Your skin’s surface temperature, normally around 86°F, drops to around 64°F during cryotherapy. (1)

How do ice baths work?

Ice baths are cold exposure using icy water.

Also known as cold plunges, ice baths seem pretty self-explanatory – you jump into some icy water and you sit there for anywhere from 1 to 10 minutes. Take your pick of receptacle: bathtub, repurposed water trough, or nearby river flowing with melting snowpack from the mountains.  

However, ice baths are a little less straightforward than you’d think, because they are usually done at home, where it isn’t easy to achieve a controlled environment. Temperature varies widely. They’re usually not supervised by a health professional. People may immerse themselves for a few seconds, or several minutes. People may choose to plunge only the legs, or everything from the neck down. 

With all of these differing variables, the results can obviously vary. Most human research in cold water immersion uses a water temperature between 40-55°F. (2)

A plastic bag of ice

What are the Health Benefits of Ice Baths vs Cryotherapy?

Cold exposure, whether from cryotherapy or ice baths (or even cold showers), can benefit muscle recovery, mental health, metabolism, and more. 

There are both physiological and psychological mechanisms behind the benefits of cold exposure. In general, the effects seem to come from increased epinephrine, norepinephrine, and endorphins, and from practicing mental resilience during stressful conditions.

Let’s explore some of the research behind these health benefits.

Side view crop anonymous slim female in light pink top and black leggings with lightweight dumbbells against gray wall
Cold exposure helps with muscle soreness and recovery after exercise

Cold Exposure for Muscle Recovery

TL;DR –

Cold therapy reduces muscle soreness after exercising when used within about an hour after exercise.

The mechanism is debated, but could be due to 1) a placebo effect, 2) the release of epinephrine/norepinephrine causing a pain-relieving effect, or 3) vasoconstriction of blood vessels, causing inflammatory and waste products to be cleared out from around cells. 

The details:

The largest meta-analysis of cold therapy for muscle recovery from exercise was done by Dr. Erich Hohenauer at the University of Fribourg in Switzerland. His group reviewed 36 studies on how cold therapy affects post-exercise recovery for muscle tissue.

Overall, cold exposure within 1 hour of exercising reduces subjective muscle soreness for up to 48 hours after exercise. That is, exercisers self-report feeling less sore after cold exposure for up to 48 hours, compared to the exercisers who did not have any cold exposure. 

There was not a significant difference in markers of muscle fatigue (lactate, creatine kinase) or markers of inflammation (C-reactive protein, IL-6) between the cold exposure and non-cold exposure groups. This suggests that the reduced muscle soreness could be due to a placebo effect, rather than any local physiological effect (Hohenauer, E. et al. (2015). The effect of post-exercise cryotherapy on recovery characteristics: a systematic review and meta-analysis. PloS one.) 

However, other studies suggest that the reduced muscle soreness could stem from decreased muscle tissue temperature, which slows down nerve conduction, along with the release of epinephrine/norepinephrine, creating a pain-relieving effect in the brain (3) 

Another mechanism for reduced muscle soreness is that the release of norepinephrine causes vasoconstriction (narrowing of blood vessels). This changes the pressure gradient between the blood vessels and the interstitial space (the space between blood vessels and cells).

This change in pressure acts like a compression sock or sleeve, causing fluid in the interstitial space to be re-absorbed into the bloodstream, thus decreasing swelling and decreasing inflammatory molecules in the area. (4)

Cold Exposure for Mental health

TL;DR –

Deliberate cold exposure can increase resilience and your ability to cope with stress. This effect comes about when the stress response is activated, epinephrine, norepinephrine, and endorphins are released, and you train your mind to remain calm despite these stressful conditions.

The details:

Cold exposure is a stressful event. However, a certain level of stress is actually beneficial to your body! Purposely activating your body’s stress response while teaching your mind that you are safe leads to great benefits for your mental health and nervous system.

Woman Walking on a Lakeshore
Cold exposure improves mental health by increasing tolerance to the body’s stress response

Uncomfortably cold temperatures cause your brain to release norepinephrine and beta-endorphin. This signal says “Stress!!” and tries to mobilize your body to get out of the stressful situation – fight or flight. (Read more here: How Stress Works (Part 1): Your Body’s Stress Response Pathway + How To Understand It)

When you respond with calm, self-regulation, resilience, and you stay in the stressful situation while assuring yourself of your safety, this improves mental health, improves stress-coping mechanisms, and reduces symptoms of depression (4) (5) (6)

Cold water immersion of just the face has been shown to offer similar benefits in reducing depressive symptoms, by activating the vagus nerve. (7) (Read more here: Vagus Nerve 101: How to Improve Vagal Tone for Better Gut, Heart, + Mental Health)

A phone with the image of a charged battery
Cold exposure increases energy levels through activation of the sympathetic nervous system

Cold Exposure for Increased Energy Levels

TL;DR –

Cold exposure can increase energy levels due to the activation of the sympathetic nervous system and release of epinephrine and norepinephrine, and their ability to sync your circadian rhythm.

The details:

When you stress your body by exposing it to cold water or cold air, you release epinephrine and norepinephrine. These neurotransmitters promote attention, alertness, and energy. They do this by diverting blood flow to the muscles, increasing heart rate and blood pressure, and freeing up glucose to be used for fuel. (8)

In addition, cold exposure can help modulate your circadian rhythm by affecting your body temperature. 

Epinephrine and norepinephrine cause vasoconstriction, or tightening of blood vessels. Vasoconstriction decreases blood flow to the skin and prioritizes blood flow to internal tissues to try and protect your core body temperature. So, when cold exposure isn’t too prolonged, your body actually responds by raising your core body temperature. 

When you use cold exposure in the morning, it helps modulate your body’s circadian rhythm. A strongly synced circadian rhythm is like your body’s built-in alarm clock, allowing you to feel more energized in the morning and ready for sleep when it’s time for bed.

Part of your circadian rhythm involves raising your body temperature in the morning and lowering your body temperature before bed. So facilitating this natural rise and fall in temperature helps sync your circadian rhythm and improve energy levels and sleep.  (9) (10)

Cold therapy for Enhanced Metabolism

TL;DR –

Cold exposure leads to increased brown fat and improved blood glucose and fat metabolism, both of which can contribute to decreased adiposity and increased lean body mass.

The details:

Cold exposure naturally causes your body to try and get warmer. It does this in two ways. 

The first is “shivering thermogenesis,” where your body involuntarily starts shivering to generate heat. 

Flames Coming out of Stone Furnace
Cold exposure increases your body’s “furnace” of brown fat

The second is “non-shivering thermogenesis,” where specialized tissue – brown adipose tissue – acts like a little furnace, creating heat in the body. Brown adipose tissue (aka, brown fat) is full of tons of mitochondria, so it is a very metabolically active tissue. Increasing the amount of brown fat you have increases your metabolic rate, which is the baseline amount of calories your body burns. (11)

In addition to increased brown fat, cold exposure also seems to cause hormonal changes that increase metabolic health.

Cold exposure decreases levels of insulin in the blood while simultaneously increasing insulin sensitivity. This means that tissues are able to take up blood glucose to be metabolized more efficiently, which is protective against insulin resistance, diabetes, and other metabolic diseases. (12)

Cold exposure also increases levels of adiponectin, a hormone that increases insulin sensitivity, increases metabolism of glucose and lipids (fats), and promotes the biogenesis of mitochondria. All of these effects allow adiponectin to be protective against diabetes, atherosclerosis, and other age-related diseases. (13) (14)

Cold therapy for Nervous system regulation

TL;DR –

Acutely, cold exposure activates the sympathetic nervous system, offering pain relief, focus, and energy levels.

Long-term, cold exposure helps re-activate the parasympathetic nervous system, and health measures such as higher HRV.

The details:

As mentioned earlier, cold exposure is a stressor that acutely activates the sympathetic nervous system, a.k.a. the fight or flight response. This causes the release of epinephrine, norepinephrine, and dopamine, as well as the release of endorphins. Some acute effects of these hormones and neurotransmitters are pain relief and increased focus, attention, and energy levels. (15)

After activating the sympathetic nervous system, it’s beneficial to move your body back into a parasympathetic state (the rest-and-digest system). Cold exposure helps reactivate the parasympathetic nervous system long term. When you practice cold therapies repeatedly, it improves HRV, a measurement of parasympathetic activation (for more on HRV, see here: Vagus Nerve 101). (16) (17)

What are the downsides of cryotherapy?

One big downside of cryotherapy is it’s expensive. The average cost for one 3-minute whole body cryotherapy session at a health facility or spa is between $30 to $50.

Another downside is the risk of frostbite and risk of hypothermia. 

Finally, cryotherapy should not be attempted with certain health conditions or medical conditions, such as cardiac arrhythmia, myocardial hypertrophy, coronary artery disease, or untreated high blood pressure. This is because cold exposure increases cardiac strain. (18)

Those with cold-sensitive conditions like Raynaud’s syndrome should also use caution with cold therapies. 

What are the downsides of ice baths? 

Similar to cryotherapy, ice baths pose a risk of hypothermia. However, it is almost impossible to get frostbite from ice baths (because the freezing temperature of human tissue is lower than the freezing temperature of fresh water). 

Another possible downside of ice baths is that the conditions can be very hard to control. Some people may use water temperatures that are excessively cold and cause injury. In reality, you can reap the same benefits of cold exposure with less extreme temperatures; all you need is an “uncomfortable” temperature, as this will activate your body’s sympathetic nervous system. (5)

Which is the better option: ice baths or cryotherapy?

Key Differences Between Ice Baths vs Cryotherapy

Here is a handy chart for a side-by-side comparison of ice baths vs cryotherapy:

CryotherapyIce Bath
MediumAirWater
Typical temperature-150°F to -280°F20°F to 55°F
Typical duration2-3 minutes3-15 minutes
Effect on skin surface temp.Decreases by ~19°F (goes from 86°F to 64°F)Decreases by ~13°F (goes from 86°F to 73°F)
Effect on core body temp.Decreases by 0°F (typically no change)Decreases by 0 to 0.7°F (typically very small change)
SettingHealth facility or spaHealth facility or spa, OR at home, OR in nature
Typical cost$30-50 per 3-minute session at a facility (cannot DIY at home)$20-30 per one-hour session at a facility,
which usually includes sauna as well
OR free to DIY at home
Health benefitsDecreased muscle soreness
Increased mental resilience and stress coping
Increased energy levels, attention, and focus
Enhanced metabolic health
Improved nervous system regulation
Health risksRisk of frostbite
Risk of hypothermia
Risk of other cold injury
Risk of hypothermia
Risk of other cold injury
Ice baths vs cryotherapy side-by-side comparison

Ice Baths vs Cryotherapy: Which One is Right For YOU?

Ice baths vs. cryotherapy? In the end, only you can decide what your personal preference is. Learn about the health benefits, the costs, and any health risks, and you can make an informed decision. 

Whether you’re trying ice baths or cryotherapy for better exercise recovery, improved mental health, increased energy levels, a more regulated nervous system, or enhanced metabolism (or maybe all of the above!), they are a great, DIY tool you can try to improve your health.

Let me know what your approach is in the comments!

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References
  1. Banfi, G. et al. (2010). Whole-body cryotherapy in athletes. Sports Medicine.
  2. Hohenauer, E. et al. (2015). The effect of post-exercise cryotherapy on recovery characteristics: a systematic review and meta-analysis. PloS one.
  3. Wilcock IM, et al. (2006). Physiological response to water immersion. A method for sport recovery? Sports Medicine.
  4. Tipton, M. et al. (2017). Cold water immersion: kill or cure? Experimental physiology.
  5. Crum, A. J. et al. (2013). Rethinking stress: the role of mindsets in determining the stress response. Journal of personality and social psychology.
  6. Huttunen P, et al. (2004) Winter swimming improves general well-being. Int J Circumpolar Health.
  7. Bonaz B, et al. (2016). Anti-inflammatory properties of the vagus nerve: potential therapeutic implications of vagus nerve stimulation. J Physiol.
  8. Goldstein DS. (2010). Catecholamines 101. Clin Auton Res.
  9. Okamoto-Mizuno, K., & Mizuno, K. (2012). Effects of thermal environment on sleep and circadian rhythm. Journal of physiological anthropology.
  10. Šrámek, P., et al. (2000). Human physiological responses to immersion into water of different temperatures. European journal of applied physiology.
  11. van der Lans, A. A., et al. (2013). Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. The Journal of clinical investigation.
  12. Orava J, et al. (2011) Different metabolic responses of human brown adipose tissue to activation by cold and insulin. Cell Metab.
  13. Imbeault P, Dépault I, Haman F. (2009) Cold exposure increases adiponectin levels in men. Metabolism.
  14. Espeland, D. et al. (2022). Health effects of voluntary exposure to cold water–a continuing subject of debate. International journal of circumpolar health.
  15. Castellani, J. W., & Young, A. J. (2016). Human physiological responses to cold exposure: Acute responses and acclimatization to prolonged exposure. Autonomic Neuroscience.
  16. Bleakley, C. M., et al. (2014). Whole-body cryotherapy: empirical evidence and theoretical perspectives. Open access journal of sports medicine.
  17. Buchheit, M. et al. (2009). Effect of cold water immersion on postexercise parasympathetic reactivation. American Journal of Physiology-Heart and Circulatory Physiology.
  18. Ikäheimo, T. M. (2018). Cardiovascular diseases, cold exposure and exercise. Temperature.

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How Stress Works (Part 2): 4 steps to optimize the stress response pathway + feel better https://rvy.ayu.mybluehost.me/how-stress-works-part-2-optimize-stress-response-pathway/?utm_source=rss&utm_medium=rss&utm_campaign=how-stress-works-part-2-optimize-stress-response-pathway https://rvy.ayu.mybluehost.me/how-stress-works-part-2-optimize-stress-response-pathway/#respond Tue, 20 Feb 2024 18:19:58 +0000 https://rvy.ayu.mybluehost.me/?p=1353 Learn how to optimize the stress response pathway and take care of your body with the best science-backed, functional health tools. From the mind-body connection and the dual role of exercise, to stress-reducing foods and effective sleep hygiene, you’ll find everything you need for holistic stress management. (If you missed part one – How Stress...

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Learn how to optimize the stress response pathway and take care of your body with the best science-backed, functional health tools. From the mind-body connection and the dual role of exercise, to stress-reducing foods and effective sleep hygiene, you’ll find everything you need for holistic stress management.

(If you missed part one – How Stress Works (Part 1): Your Body’s Stress Response Pathway + How To Understand It – go back and learn how the body’s stress response pathway works, and how to become more in tune with your own body and health.

How to tell if the body is stressed

In part one, “How Stress Works (Part 1): Your Body’s Stress Response Pathway + How To Optimize It,” you learned how the body’s biological stress response pathway works, and some symptoms that can result when it’s out-of-whack or overburdened. Now we’ll talk more about some tools you can use to assess your body’s status and tips to feel better!

Lab tests and other clinical assessments can measure stress biomarkers and chronic activation of the HPA-axis. In addition, it is so beneficial to become attuned to your own body. It pays dividends to learn the cues of your body: what feels normal and healthy for you and what feels out-of-whack.

Stress and body weight

Two important organs that control body temperature are brown adipose tissue (aka, brown fat) and the thyroid gland. Both of these organs are affected by stress in different ways, depending on the type of stress. For example, acute forms of stress such as cold exposure (e.g., cold plunges) can actually increase formation of brown fat and increase levels of T3 thyroid hormone, leading to better body temperature regulation and a higher metabolic rate (Read more here: How to cold plunge safely – for healthy weight and less stress)  (10).

However, chronic stress can indirectly lead to low body temperature due to decreased thyroid function. Chronic activation of the stress response pathway is shown to decrease function of both the thyroid gland and brown fat, which can be reflected with lower core body temperature levels. This might also look like cold hands and feet, or general intolerance to cold. (11, 12).

Stress and body temperature

Two important organs that control body temperature are brown adipose tissue (aka, brown fat) and the thyroid gland. Both of these organs are affected by stress in different ways, depending on the type of stress. For example, acute activation of the stress response pathway such as cold exposure (e.g., cold plunges) can actually increase formation of brown fat and increase levels of T3 thyroid hormone, leading to better body temperature regulation and a higher metabolic rate (Read more here: How to cold plunge safely – for healthy weight and less stress)  (10).

However, chronic stress can indirectly lead to low body temperature due to decreased thyroid function. Chronic stress is shown to decrease function of both the thyroid gland and brown fat, which can be reflected with lower core body temperature levels. This might also look like cold hands and feet, or general intolerance to cold. (11, 12).

Stress and mood

We know that trauma is associated with high cortisol levels, and also that high cortisol increases rates of depression and suicide. (13)  If you find that you are quick to anger or yell, or you are frequently anxious about things you can’t control, these could be signs of high cortisol levels.

Lab tests for stress

Physical measurements are the easiest, least-invasive way to assess chronic stress and HPA activation. In addition, these are data you can collect on your own at home to build a picture of what’s normal for you and your stress response pathway.

Why test cortisol levels to optimize the stress response pathway

If you are suffering from symptoms that you think are related to HPA-axis dysfunction, you may benefit from hormone testing for cortisol and other stress hormones. Symptoms might include: chronic stress, sleep issues and fatigue, chronic/unexplained pain, and/or blood sugar issues.

  • High cortisol levels may be due to blood sugar dysregulation, excessive stress, pain, sleep issues, polycystic ovary syndrome, or a pituitary or adrenal disorder like Cushing’s disease.
  • Low cortisol levels may be due to an adrenal disorder such as Addison’s disease, or due to constant chronic stress causing the adrenal gland to downregulate its production of cortisol.

(Please always remember that only YOUR qualified healthcare provider can interpret your results and give you personalized care. Information on this website does NOT qualify as personal/health/medical advice.)

In addition, clinical lab tests can give you more insight into your stress response pathway. If you want to understand your own baseline health and hormone levels, you can consider asking your healthcare provider for the following blood tests, or consider testing them using at-home kits:

Cortisol Morning Blood Test
  • A cortisol serum test drawn in the morning is the standard place to start. First, because it’s usually the cheapest and most accessible. Second, because cortisol levels are highest in the morning, then drop throughout the day. 
Salivary cortisol and DUTCH test:
  • Cortisol in the saliva represents the unbound, bioactive levels of cortisol available in the body. It is a less invasive procedure, but the downside is that many traditional healthcare providers do not offer this testing option. There are many online “DIY” test kits that you can order to assess your saliva at home.
  • The DUTCH test is a type of salivary cortisol test that measures cortisol five times throughout the day. First, immediately upon waking; second, 30 minutes after waking; third, 60 minutes after waking; fourth, before dinner (around 4-5pm); and last, before bed (between 10pm-midnight).
    • This test is beneficial because it shows the circadian fluctuations in cortisol. What’s more, it can help give answers if your serum cortisol test comes back in a normal range, but you still have symptoms that you think are tied to HPA dysfunction.
Urinary cortisol
  • Similar to salivary cortisol, urinary cortisol is usually measured multiple times over 24 hours to give a picture of circadian cortisol levels and the cortisol awakening response. (14, 15)
  • You should also remember that cortisol is circadian – meaning, it fluctuates throughout the day. So a single morning blood draw can give you an understanding of your benchmark cortisol levels, but it cannot give you a full picture of your hormone levels and the stress response pathway.

Optimizing the stress response pathway with mind-body connection

Is the mind-body connection proven? What the research says

There is no denying that your mind affects your body. Research is increasingly showing how this happens on a biological level. (16)

Mind-body connection therapies are designed to activate the parasympathetic nervous system, and inactivate the sympathetic (fight-or-flight) nervous system. Mind-body therapies such as biofeedback and mindfulness modalities can effectively treat headaches, chronic pain, anxiety, hypertension, and more. (17)

How does biofeedback therapy optimize the stress response pathway?

Biofeedback is a therapeutic technique to help you gain awareness and control over physiological processes, such as muscle tension, breathing, and heart rate. Similar to physical therapy, this requires practice and consistency to train your mind to control these functions that were once thought of as involuntary.  (17) 

Biofeedback therapy usually involves hooking up to equipment to monitor your internal processes. These allow you to observe what’s going on inside your body in real time. Some examples include heart rate monitors, respiratory rate monitors, or electrodes on the surface of the skin to monitor muscle activity. This equipment is visualized on a screen to help you become aware of the associated sensations, and over time bring these biological processes under your voluntary control. (17)

Biofeedback training has been shown to help treat anxiety, chronic pain, tension headaches, hypertension, urinary incontinence in females, and even ADHD. (18)

What can mindfulness and meditation do to optimize the stress response pathway?

Jon Kabat-Zinn is a leader in using mindfulness and meditation to treat chronic pain and disease. It’s easy to be skeptical that something as simple as mindful meditation could have any effect on our health. Kabat-Zinn illustrated this incredulity when he said in an interview, “People might say ‘What are you talking about? Meditation? Yoga? Give me a break!’”

However, meditation and mindfulness have clinically-proven effects on mental conditions such as anxiety, pain, depression, stress, and even chronic diseases like fibromyalgia, cancer, cardiovascular disease, and hypertension. (19) 
In mindfulness meditation practices, it differs from biofeedback in that you’re not trying to control physiological processes. Rather, you’re trying to be present and just pay attention to your internal state, and calm your emotions toward that internal state. And it shows that the way you think and feel toward your body and your illness have a profound effect on your health – patients report lower pain scores, decreased stress, depression, and anxiety, and improved biomarkers such as blood pressure and HRV. (20)

How does exercise help optimize the stress response pathway?

Exercise releases endorphins and dopamine

Many benefits of exercise on stress and mental health can be attributed to the natural production of endorphins, which have natural pain-relieving properties, as well as activating reward circuits in the brains. Regular physical activity reduces fatigue, improves cognitive function, improves sleep, and stabilizes mood. (21) There is also a component of exercise-induced stress that can be beneficial to our bodies. This is called hormesis, and when our bodies are challenged with a moderate amount of stress, it improves health and longevity in many ways (and that’s a whole post for another day!) (43)

How does exercise trigger the stress response?

While a certain amount of stress via exercise can be healthy, studies show that some exercise can tip the balance too far. Intense cardio activities, such as HIIT exercise, can excessively elevate cortisol for some people. (22) While some may benefit from this type of exercise with proper nutrition, hydration, and rest, many people cannot tolerate this rise in cortisol and can actually suffer detrimental effects on hormones, musculoskeletal structures, or heart health. 

Depending on your lifestyle, activity levels, and hormone levels, intense cardio exercise should sometimes be avoided in favor of more low intensity or low impact movements, such as walking, yoga, or pilates, or weight training. This comes back to knowing and being in-tune with your own body — you can learn your internal cues to know what is helping optimize your body’s stress response pathway, and what is harming it.

[Read more about another stress management tool here: Cryotherapy vs Ice Bath: Which Is Better for Your Body?]

Nutrition: What foods reduce stress and anxiety?

Stress means the body needs more resources – energy, oxygen, vitamins, and minerals. However, people often reach for foods that are less nutrient-dense, more processed, and more sweet when under chronic stress. This is partly because carbohydrate-dense foods prompt the brain to make more serotonin, and this feel-good neurotransmitter can provide stress relief.  (23)

This is also partly because chronically elevated cortisol increases hormones and neurotransmitters that increase appetite and craving for energy-dense foods, like neuropeptide-Y. Simultaneously, chronically elevated cortisol decreases hormones that signal fullness and satiety, like leptin. (24) So, over time, unmanaged chronic stress can lead to increased weight gain and higher body fat. (25)

Foods that soothe and optimize the stress response pathway

Omega-3 fatty acids 

Omega-3’s can prevent increases in stress hormones and may help protect against heart disease, mood disorders like depression, and PMS. (26)

You can up your omega-3 intake with fish such as salmon and tuna, as well as quality fish oil or algae-based omega 3 supplements. 

Magnesium

Magnesium deficiency is commonly found in those with depression, post-traumatic stress disorder, anxiety disorders, ADHD, and bipolar disorder. This suggests that activation of the stress response pathway causes the body to use up more magnesium (27, 28) 

To combat this, try increasing magnesium intake through green leafy vegetables, pumpkin seeds, chia seeds, or even a magnesium glycinate supplement before bed.

Vitamin C  

Vitamin C is a common nutrient deficiency in stress-related disorders, like anxiety and depression. Further, supplementing with vitamin C can improve mood and provide a small antidepressant effect. Scientists think that the way vitamin C can do this is by supporting the neurotransmitter pathways for serotonin, dopamine, epinephrine, and norepinephrine. (29, 30)

Here are some of the best whole food sources of vitamin C to help up your intake and help optimize your stress response pathway: kiwi, citrus, berries, bell peppers, tomatoes, and broccoli.

Adaptogens and supplements to optimize the stress response pathway

Adaptogens are substances that claim to increase the body’s resilience to stress. While some have better scientific support than others, here are a few that have some good data behind them.

Rhodiola for stress

Rhodiola rosea is well-documented for its ability to reduce stress, fatigue, and anxiety. (31) It is still being studied for mechanism, but it’s hypothesized that rhodiola’s active compounds can interact with signals at a cellular level to blunt the effects of cortisol during stress, as well as interact with cortisol systemically to reduce its levels. (32)

Ashwagandha for stress

Ashwagandha is an herbal supplement that has been used for thousands of years in Ayurvedic medicine, which is the traditional Hindu system of medicine. There are not plentiful amounts of scientific data from human studies, but the available data does show that ashwagandha can lower cortisol, and generally reduce stress and anxiety. (33)

L-Theanine for stress

L-theanine is an amino acid that is naturally occurring in tea leaves, especially green tea. There is some evidence that supplementing with L-theanine can reduce stress and anxiety in acutely stressful situations. (34) Some reports show that L-theanine reduces the “jitters” and headaches that come along with caffeine consumption, and it can help improve focus and attention, all combining to support and optimize the stress response pathway. (35)

Sleep hygiene: How to sleep when stressed and anxious

The importance of quality sleep is pretty obvious. Similar to stress, sleep affects almost every other body system. Finding ways to sleep well, even when stressed or anxious, can therefore improve almost all other aspects of health! 

Everyone should be getting around 7 to 9 hours of quality sleep every night, and this is especially important for the proper balancing and regulation of cortisol and other stress hormones. (36)

The neuroscience of creating a bedtime routine

It might sound overly simple, but creating a consistent bedtime routine – with a few key elements – can seriously help you optimize sleep, take advantage of the stress response pathway, and improve your health. Habits and behaviors are always the first thing you should try when trying to improve your health!

Here are a few elements to remember so you can get the best zzz’s possible:

  • Go to bed at the same time every night. Your circadian rhythm (melatonin, cortisol awakening response, etc.) loves patterns and consistency.  
  • Get outside to view bright light as soon as possible after you wake up. Sunlight (or an artificial sunlight lamp) will help your body wake up and sync your circadian rhythm better than any other practice. Yep – better than exercise, better than a cold shower, better than caffeine or other stimulants. Think of this like installing a natural alarm clock into your brain; the more you do it, the easier it will be to wake up at the same time every morning
  • Avoid bright lights before bed – and all night long. Dim the lights at home for the 2 hours before bed – even better if you can turn off overhead lights and use lamps instead. The neurons connected to your eyes can sense the brightness of all wavelengths of light (not just blue light!), and they can also sense the angle of light coming into your eyes! Dim lights at a low angle signal to your brain to produce melatonin, which will help you fall asleep and stay asleep better at night.
  • NSDR. Non-sleep deep rest is a type of meditation that calms your nervous system so you can get into a relaxed parasympathetic state and facilitate better sleep. It can also be called different things: body scan meditation, Yoga Nidra. Here is a guided protocol you can try: NSDR (Non-Sleep Deep Rest) with Dr. Andrew Huberman. This is especially helpful if you wake up in the middle of the night and can’t fall back asleep.
  • (37) 

Natural sleep aids

Some people may want to try something a little extra help with sleep, beyond just behavioral changes. Here are a few science-supported tools and supplements you can try to improve sleep and help optimize the stress response pathway. 

When introducing a new supplement, add one at a time and give it a few weeks to see how your body reacts before adding in another one. (And always remember: consult with your personal healthcare provider, this is not personal/health/medical advice)

  • Magnesium. Many people across the entire population are deficient in magnesium (38) Supplementing with forms of magnesium that are gentler on the gut, like magnesium glycinate or magnesium threonate, can help improve sleep. (39) Magnesium does this through blocking certain excitatory neurotransmitters (NMDA) and activating other inhibitory neurotransmitters (GABA) to reduce brain arousal and have a relaxant effect. (40)
  • Tart cherry juice. This is an easy, safe, and super effective whole food sleep supporter! There are several good clinical trials showing that tart cherry juice before bed helps people fall asleep easier and wake up less through the night. Tart cherry juice is able to do this by increasing melatonin production, and increasing production of tryptophan (which is a precursor to melatonin). (41)
  • Chamomile or Apigenin. Chamomile tea is also an effective and safe way to support sleep. The active compound in chamomile is called apigenin. Studies have shown that chamomile tea improves sleep through reducing cortisol levels. (42)

Summary

I believe knowledge is empowering! I hope that you now feel equipped with 1. the knowledge to optimize your body’s stress response pathway 2. the tools to conquer stress and feel better. 

Whether you want to harness the power of the mind-body connection, optimize how you approach exercise, or incorporate more stress-reducing foods, let me know in the comments how you plan to use these tools to manage stress, balance your hormones, and feel better. And let me know what other content would be helpful for you to learn how to take care of your body!

References
  1. Purnell, J. Q., et al. (2009). Enhanced cortisol production rates, free cortisol, and 11β-HSD-1 expression correlate with visceral fat and insulin resistance in men: effect of weight loss. American Journal of Physiology-Endocrinology and Metabolism.
  2. Dreno B., et al. Large-scale international study enhances understanding of an emerging acne population: adult females. J Eur Acad Dermatol Venereol 2015;29:1096-106.
  3. InformedHealth.org. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. What are the organs of the immune system?)
  4. Jović, A., et al. (2017). The impact of psychological stress on acne. Acta derm Croatica.
  5. Crofford, L. J. (2015). Chronic pain: where the body meets the brain. Transactions of the American Clinical and Climatological Association
  6. Crofford, L. J. et al. (2004). Basal circadian and pulsatile ACTH and cortisol secretion in patients with fibromyalgia and/or chronic fatigue syndrome. Brain, behavior, and immunity.
  7. Schroeder, S. et al. (2017). Effectiveness of acupuncture therapy on stress in a large urban college population. Journal of Acupuncture and Meridian Studies.
  8. Lombardo, M., et al. (2022). The efficacy of vitamin D supplementation in the treatment of fibromyalgia syndrome and chronic musculoskeletal pain. Nutrients
  9. Jahangard, L. et al (2019). Omega-3-polyunsatured fatty acids (O3PUFAs), compared to placebo, reduced symptoms of occupational burnout and lowered morning cortisol secretion. Psychoneuroendocrinology.
  10. Espeland, D., et al. (2022). Health effects of voluntary exposure to cold water–a continuing subject of debate. International journal of circumpolar health.
  11. Oka, T. (2018). Stress-induced hyperthermia and hypothermia. Handbook of clinical neurology.
  12. Kioukia-Fougia, N. et al. (2002). The effects of stress exposure on the hypothalamic–pituitary–adrenal axis, thymus, thyroid hormones and glucose levels. Progress in Neuro-Psychopharmacology and Biological Psychiatry.
  13. Burke, H. M., et al. (2005). Depression and cortisol responses to psychological stress: a meta-analysis. Psychoneuroendocrinology.
  14. El-Farhan, N. et al. (2017). Measuring cortisol in serum, urine and saliva–are our assays good enough?. Annals of clinical biochemistry.
  15. Babic, N. et al. (2023). Endocrine testing protocols: hypothalamic pituitary adrenal axis. Endotext.
  16. Levine, G. N. et al. (2021). Psychological health, well-being, and the mind-heart-body connection: a scientific statement from the American Heart Association. Circulation.
  17. Frank, D. L. et al. (2010). Biofeedback in medicine: who, when, why and how?. Mental health in family medicine.
  18. Yucha C, Montgomery D. Evidence‐Based Practice in Biofeedback and Neurofeedback. Wheat Ridge: Association for Applied Psychophysiology and Biofeedback, 2008.
  19. Bonadonna, R. (2003). Meditation’s impact on chronic illness. Holistic nursing practice.
  20. Ospina, M. B. et al. (2007). Meditation practices for health: state of the research. Evidence report/technology assessment.
  21. Sprouse-Blum, A. S., Smith, G., Sugai, D., & Parsa, F. D. (2010). Understanding endorphins and their importance in pain management. Hawaii medical journal.
  22. Dote‐Montero, M. et al. (2021). Acute effect of HIIT on testosterone and cortisol levels in healthy individuals: A systematic review and meta‐analysis. Scandinavian journal of medicine & science in sports.
  23. Gonzalez, M. J., & Miranda-Massari, J. R. (2014). Diet and stress. Psychiatric Clinics.
  24. Sinha, R. (2018). Role of addiction and stress neurobiology on food intake and obesity. Biological psychology, 131, 5-13.
  25. Block, J. P. et al. (2009). Psychosocial stress and change in weight among US adults. American journal of epidemiology.
  26. Bradbury, J. et al. (2004). An adaptogenic role for omega-3 fatty acids in stress; a randomised placebo controlled double blind intervention study (pilot). Nutrition Journal.
  27. Cernak, I. et al. (2000). Alterations in magnesium and oxidative status during chronic emotional stress. Magnesium research.
  28. Botturi, A. et al. (2020). The role and the effect of magnesium in mental disorders: a systematic review. Nutrients.
  29. Sim, M. et al. (2022). Vitamin C supplementation promotes mental vitality in healthy young adults: results from a cross-sectional analysis and a randomized, double-blind, placebo-controlled trial. European journal of nutrition.
  30. Moritz, B. et al. (2020). The role of vitamin C in stress-related disorders. The Journal of Nutritional Biochemistry.
  31. Ishaque, S. (2012). Rhodiola rosea for physical and mental fatigue: a systematic review. BMC complementary and alternative medicine.
  32. Panossian, A. (2010). Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine.
  33. Pratte, M. A. et al. (2014). An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha. The Journal of Alternative and Complementary Medicine.
  34. Williams, J. L. et al. (2020). The effects of green tea amino acid L-theanine consumption on the ability to manage stress and anxiety levels: A systematic review. Plant foods for human nutrition.
  35. Haskell, C. F. et al. (2008). The effects of L-theanine, caffeine and their combination on cognition and mood. Biological psychology.
  36. Huberman, A. (2021–present). Huberman Lab [Audio podcast]. How to Optimize Fertility in Males & Females.
  37. Huberman, A. (2021-present). Huberman Lab [Audio podcast]. Toolkit for Sleep.
  38. De Baaij, J. H. et al. (2015). Magnesium in man: implications for health and disease. Physiological reviews.
  39. Zhang, Y. et al. (2022). Association of magnesium intake with sleep duration and sleep quality: findings from the CARDIA study. Sleep.
  40. Schwalfenberg, G. K., & Genuis, S. J. (2017). The importance of magnesium in clinical healthcare. Scientifica.
  41. Howatson, G. et al. (2012). Effect of tart cherry juice (Prunus cerasus) on melatonin levels and enhanced sleep quality. European journal of nutrition.
  42. Chang, S. M., & Chen, C. H. (2016). Effects of an intervention with drinking chamomile tea on sleep quality and depression in sleep disturbed postnatal women: a randomized controlled trial. Journal of advanced nursing.
  43. Kouda, K., & Iki, M. (2010). Beneficial effects of mild stress (hormetic effects): dietary restriction and health. Journal of physiological anthropology, 29(4), 127-132.

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How Stress Works (Part 1): Your Body’s Stress Response Pathway + How To Understand It https://rvy.ayu.mybluehost.me/stress-response-pathway-part-1/?utm_source=rss&utm_medium=rss&utm_campaign=stress-response-pathway-part-1 https://rvy.ayu.mybluehost.me/stress-response-pathway-part-1/#respond Tue, 06 Feb 2024 18:16:00 +0000 https://rvy.ayu.mybluehost.me/?p=1348 Learn about the physiology of chronic stress and how to optimize your body’s stress response pathway. We’ll cover the hypothalamic-pituitary-adrenal axis and how cortisol and other stress hormones affect the metabolism, immune system, circadian rhythms and more.  Then stay tuned for part two – How Stress Works (Part 2): 4 steps to optimize the stress...

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Learn about the physiology of chronic stress and how to optimize your body’s stress response pathway. We’ll cover the hypothalamic-pituitary-adrenal axis and how cortisol and other stress hormones affect the metabolism, immune system, circadian rhythms and more. 

Then stay tuned for part two – How Stress Works (Part 2): 4 steps to optimize the stress response pathway + feel better – to learn science-backed, holistic tools to stress less and feel better. 

How stress and anxiety affect the body

Picture this: you’re driving on the freeway with the kids in the backseat, your favorite playlist pleasantly playing in the background. BAM! The car in front of you slams on their brakes and your kids scream. Your heart slams in your chest, breathing quickens, senses sharpen – your body is ready to outrun a saber-tooth tiger (or in this case, respond to traffic).

This is the fight-or-flight response in action. It’s your body’s evolved response to life-threatening situations, trying to increase your odds of surviving. But what happens when traffic is smooth, the kids aren’t crying, and all is well – but you still feel jittery and anxious? That would be chronic stress, the unwelcome byproduct of modern society, where we are surrounded by constant small stressors that keep our stress hormones chronically high, like a leaky faucet.

The good news? You’re not stuck. There are tools to soothe your stressed-out system and find your happy place amidst life’s everyday stressors. 

Keep reading to learn the science behind your body’s stress response system so you can learn how to manage and optimize it. 

Definition of the stress response pathway

What is stress, physiologically speaking?

Stress is when the body activates two brain-body communication pathways:

the sympathetic nervous system and 

the hypothalamic-pituitary-adrenal (HPA) axis

When your brain senses stress – through thoughts, emotions, or physical sensations – it sends signals (hormones and neurotransmitters) along these stress response pathways to start making things right in the body again. Your body then responds with coping behaviors to address the distress. (1)

Here are some of the physiological coping responses to acute stress:

  • ↑ Increased alertness, vigilance, and focus 
  • ↑ Increased heart rate, respiratory rate
  • ↻ Shifting of oxygen, nutrients, and energy to the brain as well as any stressed body part (e.g., a broken leg)
  • ↓ Reduced sensation of pain
  • ↓ Reduced “rest-and-digest” functions, such as digestion, reproduction, growth, and immunity
  • (2)

We *want* these things to happen in an acutely stressful situation! (e.g., a saber-tooth tiger is chasing you, you break a bone, you get an infection, etc.) These adaptive responses allow your body to increase its odds of survival when faced with a life-threatening situation. But the problems really start with our modern lifestyles, in which we are under constant levels of NON-life-threatening circumstances that activate the stress response pathway – aka, chronic stress.

What is acute stress vs. chronic stress?

Acute stress is generally shorter duration and higher intensity; it lasts for a number of minutes or hours.

Examples of Acute stress: injury, surgery, illness or infection, intense exercise like sprinting or lifting weights, giving a speech/presentation, or a sudden surprise (e.g., slamming on the brakes while driving)

Chronic stress is lower intensity but much longer duration; it lasts for many hours a day over weeks or even months. (3)

Examples of Chronic stress: constant emails and notifications, work spilling out of your shift and into all hours of the day, doom-scrolling and comparisons on social media, chronic health issues, blood sugar imbalances or imbalanced nutrition (too much or too few calories are both stressors!), lack of sleep…these are all chronic stressors. 

And our stress coping mechanisms aren’t just physiological, but emotional and behavioral as well. We have control over these coping responses, and we can make intentional choices in how we respond to stressors for better health and well-being. 

In short, that’s what we need to talk about today: chronic stress and how to beat it.

First, let’s break down each part of the stress communication pathway, the HPA axis: hypothalamus, pituitary gland, and adrenal gland.

A diagram of the hypothalamus pituitary adrenal axis that releases cortisol in response to stress
Source: https://www.researchgate.net/figure/Hypothalamic-pituitary-adrenal-HPA-axis-Experiencing-an-environmental-stressor-as_fig1_261951085

Which body system does stress affect?

As mentioned above, stress affects all of our body systems through the pathway known as the hypothalamic-pituitary-adrenal (HPA) axis, as well as the sympathetic nervous system. Starting in your brain, stress leads to a cascade of reactions and hormonal secretions that tell each organ and body system how to respond.

Let’s talk about what happens at each step of the HPA axis.

What does the hypothalamus do? 

The hypothalamus, a structure deep in the forebrain, is in charge of keeping our body in homeostasis. Homeostasis is our body’s happy place: the right pH, the right temperature, the right balance of hormones, the right balance of electrolytes, the right amount of energy…the list goes on. 

When the hypothalamus senses that one of these factors is out-of-whack, it then sends a hormone down the line of the HPA axis to the next structure: the pituitary gland. (In the case of stress, the hypothalamus releases a hormone called CRH that gets sent to the pituitary gland.) (2)

What does the pituitary gland do? 

The pituitary gland is a master controller of hormones. It’s a sort of boss of many other endocrine organs, telling them when to release their hormones. For example, the pituitary gland tells when to release:

  • Metabolic hormones in the thyroid or gut
  • Sex hormones from the ovaries or testes
  • Stress hormones from the adrenal gland. This is signaled through a hormone called ACTH
  • (2)

What does the adrenal gland do?

The adrenal gland is the end of the line of the stress response pathway, the HPA axis,. This is where *the* stress hormones are released. You’ve probably heard of cortisol and epinephrine (adrenaline) before. These hormones are the main culprits responsible for the effects of stress.

The adrenal gland has two sections: the medulla and the cortex. The medulla releases cortisol, and the cortex releases epinephrine/norepinephrine. Both cortisol and epinephrine lead to the classic symptoms of the “fight-or-flight” response.

Here are a few of the effects of the adrenal hormones, cortisol and epinephrine:

  • Increased heart rate and blood pressure
  • Increased muscle tension
  • Increased blood sugar
  • Decreased sex hormone function
  • Decreased thyroid function, lowering overall metabolic rate 
  • Impaired immune response
  • Increased inflammation
    • This is a big one. Inflammation means pro-inflammatory cytokines, prostaglandins, and other chemicals are on the prowl. 
    • These are good guys in moderation, for acutely stressful conditions. But when they’re around chronically, they inhibit the immune system, decrease wound healing, contribute to gut issues, and lead to oxidative stress (which damages mitochondria and other cellular functions, contributing to aging).
  • (4)

Remember the saber-tooth tiger example – these effects are all beneficial when your body needs to mobilize quickly in a life-threatening situation! Acute stress. But these are also the responses you get with more modern-day, chronic stressors, which are everywhere. 

Whether it’s giving an important presentation at work or school, or having an argument with your spouse, or trying to file your taxes…we are constantly confronted with stressors. 
It’s vital to train your brain to respond to chronic stress in a healthy way, so that you aren’t chronically activating your stress response pathway, the HPA axis and sympathetic nervous system.

How does stress affect digestion and metabolism?

In general, stress impairs digestion and metabolism. The body’s stress pathway is designed to send resources to sympathetic pathways (“fight-or-flight”), and pause resources to parasympathetic pathways (“rest-and-digest,” like digestion, metabolism, reproduction, and immunity).

Here are some of the metabolic effects of chronic stress:

  • Blood sugar imbalances
    • Cortisol causes muscles to break down fuel to create glucose, and causes the liver and kidneys to start producing more glucose. 
    • All this glucose goes out into circulation to raise blood sugar, so that fuel can be directed to the brain, for focus and alertness, and the stressed body part, to facilitate healing 
    • Again, this is a good response for acute stress! But bad when stress is chronic, as it contributes to the following symptoms ↓
  • Increased visceral fat and fatty liver
    • High cortisol leads to high blood glucose leads to high circulating insulin. Insulin tells the body to absorb the sugar into various tissues, like muscles, fat tissue, and liver. Long term, this leads to visceral fat accumulation – because the body needs someplace to store the excess glucose (5)
  • Insulin resistance and risk of type 2 diabetes
    • With chronically high cortisol comes chronically high blood glucose. In response, the body secretes more insulin to try and “put away” the glucose (i.e., take it out of the bloodstream and store it into tissues, like muscle, fat, liver).
    • Over time, if insulin remains high constantly, those tissues stop being able to respond to it as well (a.k.a., insulin resistance). This is a beginning mechanism of type 2 diabetes. (6)
  • Impaired digestion and gut function
    • Stress has a two-fold effect on the digestive tract. It causes less digestion and absorption of nutrients in the upper gut…and more movement in the lower gut, the colon. This usually looks like irritable bowel syndrome and chronic gastrointestinal pain. (4)

How does stress affect the immune system?

There are multiple different branches of the immune system. While stress decreases immune function under some conditions, it increases immune function under other conditions.

This paradoxical effect of stress on the immune system can be explained by the difference between acute stress and chronic stress. At risk of sounding like a broken record: 

Acute stress is a survival mechanism that benefits your health, while chronic stress is a maladaptive response that generally harms your health. 

For example, you do want your immune system activated in an acutely stressful condition, like an injury, surgery, or infection. This situation would recruit immune cells to the injured or ill site, allowing repair and healing. However, you do not want your immune system activated chronically, as this leads to chronic inflammation, susceptibility to illness and infection, and autoimmune conditions, like allergies, asthma, and more. (7)

How does stress affect circadian rhythms?

You may know that circadian rhythms are important for quality sleep. But your circadian system also regulates your appetite, digestion, blood sugar, and more.  

Circadian rhythms are the tides of your body; they control the ebb and flow of sleep hormones, digestive and metabolic hormones, body temperature, and appetite. 

Your body really likes predictability and patterns. It prefers that you go to sleep at the same time each night and eat your meals at the same time each day; this allows it to release hormones in a regular pattern. (8)

Melatonin is the main hormone that helps you feel sleepy at night, and cortisol is the main hormone that helps you wake up in the morning.

When you wake up, there’s a spike in cortisol (don’t worry, a healthy spike!) and this helps you feel alert and energized throughout the day. This is called the cortisol awakening response (CAR). Your cortisol levels are highest about 30-60 minutes after you wake up, and this is a good thing. 

Disruptions in sleep interfere with your cortisol awakening response, and this leads to low energy and lack of focus. Stress can interfere with both melatonin and cortisol levels, especially low-level stressors that you subject your body to before bed (think: scrolling social media or the news under the bright light of screens. (9)

Stress and the female body

Women are more susceptible to stress than men. Due to differences in sex hormones and their cyclical nature, women respond to stress with higher spikes of cortisol and activation of different brain circuits than men. This leads to increased emotions about stress and a longer-term activation of the stress response pathway.  (10)

Women experience more stress-related digestive problems

Studies show that there is a higher incidence of digestive disorders in women than men. (11) 

One study of patients with chronic digestive pain showed that there were significant numbers of stress-related conditions. For example, women who had been physically or sexually abused, women with post traumatic stress disorder (PTSD), and women with melancholic depression. 

All of these conditions involve chronic activation of the HPA axis (the communication highway of the stress response). This suggests that a mechanism that leads to chronic digestive problems is an overactivated stress response. (12)

With aging, the difference between men and women becomes even more pronounced. In men, the stress response of the HPA axis gets weaker, or less sensitive, as they age. In women, the opposite is true! As women age, the stress response pathway gets more sensitive. This means that as women age, the stress response system gets activated more easily and more intensely. (13) 

So, as women it becomes ever more important to nurture the mind and develop healthy habits for managing stress! We’ll cover some easy and intuitive strategies and lifestyle approaches to do just that in Part 2.

Let me know in the comments what questions you have about chronic stress, and stay tuned for part two: How Stress Works (Part 2): 4 strategies to banish stress + feel better

References
  1. Miller, G. E. et al. (2007). If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans. Psychological bulletin
  2. Tsigos, C., et al. (2020). Stress: endocrine physiology and pathophysiology. Endotext.
  3. Dhabhar, F. S., & Mcewen, B. S. (1997). Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: A potential role for leukocyte trafficking. Brain, behavior, and immunity, 11(4), 286-306.
  4. Chrousos, G. P., & Gold, P. W. (1992). The concepts of stress and stress system disorders: overview of physical and behavioral homeostasis. Jama, 267(9), 1244-1252.
  5. Epel, E. S., et al. (2000). Stress and body shape: stress-induced cortisol secretion is consistently greater among women with central fat. Psychosomatic medicine.
  6. Johnson, J. D. (2021). On the causal relationships between hyperinsulinaemia, insulin resistance, obesity and dysglycaemia in type 2 diabetes. Diabetologia.
  7. Dhabhar, F. S. (2009). Enhancing versus suppressive effects of stress on immune function: implications for immunoprotection and immunopathology. Neuroimmunomodulation.
  8. Reddy S, et al.. Physiology, Circadian Rhythm. StatPearls Publishing; 2023 Jan. https://www.ncbi.nlm.nih.gov/books/NBK519507/.
  9. Gabel, V., et al. (2013). Effects of artificial dawn and morning blue light on daytime cognitive performance, well-being, cortisol and melatonin levels. Chronobiology international)
  10. Vierhapper, H., et al. (1998). Sex-specific differences in cortisol production rates in humans. Metabolism.
  11. American Physiological Society (APS). (2015, March 30). Why gastrointestinal disorders afflict women more often. ScienceDaily.
  12. Stratakis, C. A., & Chrousos, G. P. (1995). Neuroendocrinology and pathophysiology of the stress system. ANNALS-NEW YORK ACADEMY OF SCIENCES.
  13. Veldhuis, J. D., et al. (2011). Tripartite control of dynamic ACTH-cortisol dose responsiveness by age, body mass index, and gender in 111 healthy adults. The Journal of Clinical Endocrinology & Metabolism

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Can You Freeze Cooked Liver? How to Make Your Own Liver Supplements https://rvy.ayu.mybluehost.me/can-you-freeze-cooked-liver-plus-liver-supplements/?utm_source=rss&utm_medium=rss&utm_campaign=can-you-freeze-cooked-liver-plus-liver-supplements https://rvy.ayu.mybluehost.me/can-you-freeze-cooked-liver-plus-liver-supplements/#respond Thu, 01 Feb 2024 17:27:30 +0000 https://rvy.ayu.mybluehost.me/?p=1329 Close your eyes and think of liver and onions. Did you picture your grandma’s kitchen table like me? Did your stomach growl, or did you involuntarily shiver?  Whether you enjoy the distinct taste of beef liver or not, consuming this nutrient-rich organ meat is a great way to add in B vitamins, trace minerals, and...

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Close your eyes and think of liver and onions. Did you picture your grandma’s kitchen table like me? Did your stomach growl, or did you involuntarily shiver? 

Whether you enjoy the distinct taste of beef liver or not, consuming this nutrient-rich organ meat is a great way to add in B vitamins, trace minerals, and phytonutrients. 

Learn how to make your own superfood liver “supplement” to help you get in more liver if you don’t enjoy the taste. Read on for how you can freeze cooked liver for best results, and how to prepare it – my favorite way – as DIY liver supplements.

A graphic with a person holding a picture of an illustrated cartoon liver with a thumbs-up

Intro

Beef liver is an organ meat that has long been consumed in traditional cultures around the world, but it has only recently begun to make a comeback in Western diets. 

If you appreciate the wisdom of “eating what your great grandma ate,” you’ll be more excited about jumping on the liver train. 

However, with its strong metallic taste and exceptionally smooth texture, some people may not prefer cooking liver and eating it plain. 

If this sounds like you, you can try making liver supplements! No, I’m not talking about dehydrating liver and making it into powdered and encapsulated form – I’m talking about something much simpler. We’re going to cover how to cook liver, slice it into “pill-sized” small portions, and freeze it to consume as needed.

How to choose quality beef liver

When you are sourcing raw beef liver for your own consumption, it’s important to take into account the quality of the meat. The best quality beef is grass-fed and grass-finished, also known as pasture-raised.

In a review article from Duke University and Utah State University, researchers discuss the health benefits of grass-fed beef. 

Compared to meat from conventional grain-fed animals, grass-fed beef is significantly higher in: 

  • Omega-3 fatty acids
  • Vitamin A
  • Vitamin E
  • Phytonutrients such as terpenoids, polyphenols, and carotenoids
  • Antioxidants

Phytonutrients and antioxidants are usually more associated with plants, and they have a whole host of anti-inflammatory, anti-cancer, and heart-healthy benefits. (1) 

In contrast, conventionally-raised livestock live in high-density feedlots and are fed diets mostly of corn and soy, which are low in phytonutrients. This diet increases the ratio of omega-6’s to omega-3’s in the meat. A high ratio of omega-6 to omega-3 fatty acids is associated with cardiovascular disease, inflammatory diseases, and autoimmune diseases. (2) (3)

(Important note: I understand it can be cost-prohibitive and inconvenient to choose grass-fed or pastured meat over conventional meat. I think it’s not worth stressing over the source of your meat, (because stress is probably worse for your health than anything). If you can just choose grass-fed meat here and there when you are able to, this can still benefit the overall quality and nutrition of your diet!)

Where to find fresh liver

High-quality liver may be difficult to find at your local grocery store. Luckily, there are increasingly more accessible sources of grass-fed beef, from local farms selling direct-to-consumer to natural grocers like Sprouts. 

I’m located in Northern Utah and I love to buy raw beef liver from Christiansen Family Farm (not affiliated, just a happy customer!) They do drop-offs/pick-ups of meat orders in various locations, so it’s more convenient than driving down to their farm. Try looking up a farm in your area, or visiting a local farmer’s market and talking to the farmers there!

What is the nutritional value of liver?

Liver, aka nature’s multivitamin, contains a plethora of essential nutrients – from protein, to trace minerals, to all of the B vitamins. Here are just a few stand-out nutrients that liver is rich in:

  • High-quality protein
    • Liver is a complete protein source, meaning it contains all 9 essential amino acids, and thus can be used by your body to build muscle and other lean tissue. Protein from liver is also easy for your body to digest and assimilate. (4)
  • Iron
    • Iron plays a crucial role in forming red blood cells and transporting oxygen around your body. (5) This may be one reason why some people report feeling an energy boost after consuming liver!
  • Copper
    • You use copper in your body as an enzyme cofactor in energy metabolism, nerve transmission, and defense against oxidative stress. (6)
  • Choline
    • Choline is super important for brain function – memory, mood regulation, and more. Choline is also found in all of the cell membranes of your body. (7)
  • Vitamin B12
    • Vitamin B12 helps the body create red blood cells by facilitating proper DNA synthesis. It’s also important for brain functions like mood and memory. (8)
A woman's hands putting a bag of frozen meat into the freezer

Can you freeze cooked liver?

Yes, you can freeze cooked liver!

It’s as simple as cooking it, letting it cool, removing excess moisture, flash-freezing on a tray, and then packaging it into airtight containers. 

Read on for step-by-step details on how to freeze cooked liver, and how to make your own DIY liver supplements.

1. Preparing Liver 

How to clean and prepare liver:

The first step is to rinse the liver and then trim any unwanted portions, such as any excess fat, tough connective tissue, or membranes. 

How to soak beef liver before cooking:

Beef liver has a distinct taste and texture. It’s not for everyone, so soaking is an optional step to mute its strong flavor. This helps even if you’re making the DIY liver supplements because it reduces the metallic aftertaste.

  • Option 1: Salt Water
    • You can soak beef liver in a bowl of cold water with 1 Tablespoon of salt added for 1 hour in the refrigerator.
  • Option 2: Acidic Water
    • You can soak beef liver in a bowl of cold water with 1 Tablespoon of lemon juice or vinegar added for 1 hour in the refrigerator 
  • Option 3: Milk.
    • Alternatively, you can soak beef liver in a bowl of cold milk for 1 hour in the refrigerator, (or can soak in milk up to overnight). 

After soaking, be sure to pat the liver dry with paper towels to remove excess moisture!

2. Cooking and Cooling Liver

How to cook liver

What’s the best way to cook liver? You can use various methods, but for our purposes of making DIY liver supplements, two of the easiest methods are pan-frying and Instant Pot. 

  • Option 1: Pan fry:
    • Heat a frying pan to medium-high heat. Add butter, ghee, or oil to the pan and then add the liver. Sprinkle with good-quality sea salt. Cook for 3 to 4 minutes on each side, until medium well and liver is just slightly pink inside. Take off the pan and let the liver cool to room temperature before moving on to the next step.
  • Option 2: Instant Pot
    • Pressure cook on high for 5 minutes. Then allow the pressure to naturally release for at least 10 minutes. Remove from the instant pot and allow the liver to cool to room temperature before moving on to the next step.

How long do I cook liver? 

For the best taste and to prevent that metallic aftertaste, I recommend cooking liver to medium well. Overcooking liver will cause it to be dry and taste much more metallic, as it cooks out most of the moisture and concentrates the iron. 

(Please also note that food safety recommendations dictate cooking liver to a safe temperature, or well done. For liver and other organ meats, this would be an internal temperature of 160°F.  As with any meat, there is an increased risk of foodborne illness from consuming raw or undercooked meat.)

What color should liver be when it’s cooked?

For medium well, the color of the liver should be ever-so-slightly pink inside. For well done, the liver should be completely brown inside.

3. Flash Freezing Liver and Portioning into Supplements 

After your cooked liver has cooled to room temperature, you can lay it on a baking sheet with parchment paper or a silicone baking mat. Pop it into the freezer for a couple of hours until frozen hard. 

Once it’s hardened, it will be easier to cut it into slices for your DIY liver supplements. 

Cube the liver into small portions, about ¼ inch cubes or smaller (try to cut them into a size that will be easy for you to swallow – think “pill-sized.”)

4. Freezing for Long Term Storage

Now you’ll portion out your liver “supplements” and package them into freezer-safe containers or bags, removing as much air as possible. 

I like to put a few smaller portions into small ziploc bags and then put those bags into one or two big heavy-duty freezer bags. Then don’t forget to label it with the type of meat and the date!

The science behind freezing meat:

Freezing food is great for food safety because it puts the brakes on any bacterial growth. However, it doesn’t actually kill any bacteria that are already present, so that’s why it’s important to cook meat to a safe temperature.

When you freeze meat, it creates ice crystals. These ice crystals expand during the freezing process and can break the cell walls of the meat, so later when it’s thawed again, the texture can become mushy. Any excess moisture causes more ice crystals, so remember to pat the liver dry with paper towels after cooking.

How do I avoid freezer burn?

Freezer burn is caused when food is exposed to cold air, and the moisture is drawn out of the food and re-frozen on its surface. (For you food science nerds, this is called sublimation.)

You can avoid a lot of this frosty unpleasantness by removing excess air and using the proper storage: airtight containers, freezer-safe bags, or tightly wrapped plastic wrap or aluminum foil. 

How long does liver keep in the fridge? In the freezer?

Shelf life of cooked liver in the freezer:

You can freeze liver for around three to four months. Longer than that is still safe from a food safety standpoint, but you risk freezer burn and losing a good texture.

Shelf life of cooked liver in the fridge:

In the fridge, cooked liver only lasts a couple of days (1-2 days is safest.)

Raw beef liver slices on a cutting board

How to consume your liver supplements

This method of making your own liver “supplements” lets you control the cost, size, and amount of liver you consume. It’s much cheaper than buying desiccated or powdered liver pills, which often have additional ingredients, or use solvents in the manufacturing process, or outsource their manufacturing to some anonymous white-label factory in another country.

(And as always, before you take any new supplements or make big dietary changes, it’s a good idea to consult your healthcare provider, not just a lady on the internet ?)

How do I consume my DIY liver supplements?

Just swallow your DIY liver supplements with a glass of water, just like any other pill or supplement!

How often should I consume my DIY liver supplements?

You can take 4 to 6 liver “pills” with a meal every day. Depending on how large you sliced your DIY liver supplements, this will give you about 20g of liver, full of whole-food nutrients that are easy for your body to assimilate. 

4-6 liver supplements (20g of cooked liver) will provide approximately:

  • 5 g of protein 
  • 1 mg of iron (12.5% of the RDI for males, 5.5% of the RDI for females)
  • 16 mcg of vitamin B12 (250% of the RDI)
  • 1400 mcg of vitamin A (150% of the RDI)
  • 75 mg of choline (14% of the RDI)
  • 2 mg of copper (250% of the RDI)

Bonus: 10 Liver Healing Foods

Foods that support the liver provide the raw materials for your liver to keep producing its own antioxidants and detoxification enzymes. Here are a few liver healing foods you can try adding in to your diet:

  • Bitter-rich vegetables (e.g., cranberries, grapefruit, argulua, spring greens)
  • Cruciferous vegetables (
  • Berries
  • Celery
  • Garlic
  • Turmeric
  • Onions
  • Sulfur-rich foods (e.g., beef, tuna, eggs, cabbage, spinach)
  • Dandelion tea
  • Plenty of water!

(9) (10)

Summary

Can you freeze cooked liver? Yes! My favorite way to consume liver is to cook and freeze it into your own DIY liver supplements. It’s an easy and convenient way to access the nutritional benefits of liver, especially if you don’t love the taste.

Let me know in the comments if you try making your own DIY liver supplements!

Pin It for Later

A graphic that says "How to make your own DIY liver supplements plus 10 liver healing foods"
References
  1. Van Vliet, S. et al. (2021). Health-promoting phytonutrients are higher in grass-fed meat and milk. Frontiers in Sustainable Food Systems.
  2. Daley, C. A., Abbott, A., Doyle, P. S., Nader, G. A., & Larson, S. (2010). A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef. Nutrition journal.
  3. Simopoulos, A. P. (2002). The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine & pharmacotherapy.
  4. Day, L., et al (2022). Food proteins from animals and plants: Differences in the nutritional and functional properties. Trends in Food Science & Technology.
  5. National Institutes of Health. (2022). Iron fact sheet for consumers – office of dietary supplements (ODS).
  6. National Institutes of Health . (2022). Copper fact sheet for consumers – office of dietary supplements (ODS).
  7. National Institutes of Health . (2022). Choline fact sheet for consumers – office of dietary supplements (ODS).
  8. National Institutes of Health . (2022). Vitamin B12 face sheet for consumers – office of dietary supplements (ODS).
  9. Miękus, N., et al. (2020). Health benefits of plant-derived sulfur compounds, glucosinolates, and organosulfur compounds. Molecules.
  10. González-Castejón, et al. (2012). Diverse biological activities of dandelion. Nutrition reviews,

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Red Light Therapy: How to Use It to Improve Your Gut Health https://rvy.ayu.mybluehost.me/red-light-therapy-gut-health/?utm_source=rss&utm_medium=rss&utm_campaign=red-light-therapy-gut-health https://rvy.ayu.mybluehost.me/red-light-therapy-gut-health/#respond Wed, 31 Jan 2024 16:56:05 +0000 https://rvy.ayu.mybluehost.me/?p=1308 Everyone seems to be using red light in recent years, from your physical therapist to that skincare influencer you follow on Instagram. From getting rid of acne and healing injuries to modulating circadian rhythms and improving the immune system… red light seems to heal anything that ails you! But what is backed by science, and...

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Everyone seems to be using red light in recent years, from your physical therapist to that skincare influencer you follow on Instagram. From getting rid of acne and healing injuries to modulating circadian rhythms and improving the immune system… red light seems to heal anything that ails you! But what is backed by science, and what still needs further research?

We’ll talk about how red light therapy works, what the difference is between red light and infrared light, the physiological mechanisms of red light in the human body, and how red light can improve gut health.

What is Red Light Therapy?

Red light therapy is often used as a catch-all term for any low-level light therapy, which includes near-infrared light and infrared light therapy. (Other terms include low-level laser therapy and photobiomodulation). 

Red light therapy has gained popularity in recent years as a holistic approach to improving skin cells, gut health, the immune system, and many other potential benefits to overall health.

Despite being used interchangeably, red light, near-infrared light, and infrared light are all different wavelengths. They all penetrate your skin and into the body to different extents, and so they each have different biological effects

Need a visual reminder? Let’s go back to 7th-grade science class and remember that chart of the electromagnetic spectrum. In the middle of the spectrum is visible light. This tiny slice is the light energy that our eyes can see. The wavelength just longer than that is infrared light. And remember longer wavelength = lower energy. 

Down at the other end of the spectrum is UV light, which is higher energy and more damaging to the human body.

(1)

A diagram showing wavelengths of light, highlighting the infrared portion of the spectrum
Image source: https://www.azooptics.com/Article.aspx?ArticleID=1666

What is Red Light?

Red light refers to a type of energy that is part of visible light. When you see light that appears red in color – from the setting sun or an warm-tinted lamp – that’s red light.

Red light has a wavelength between 630nm to 700nm. It is visible to our eyes.

Red light can penetrate the skin barrier, but not as deeply as near infrared light. (1)

Red light therapy devices are commonly used for skin concerns: for example for scars, acne, or wound healing. Many devices combine both red light and infrared energy in one.

What is Infrared Light?

Infrared light is a type of energy that is invisible. You can’t see it, but you can feel it as heat. You can feel infrared energy from the heat of the sun, a campfire, or a radiator. 

Infrared energy has a wavelength between 750nm to 1,000,000nm. It’s broken down into near-infrared, middle-infrared, and far-infrared. Within these, near-infrared light is the “sweet spot” that penetrates through the skin and into the body the most deeply, between 760 to 1400nm.  (1) (2)

Infrared light therapy devices such as infrared saunas usually use near-infrared light wavelengths (middle- and far-infrared light are much less common). There are also devices that combine both red light and infrared energy in one.

Infrared light therapy devices are typically used to penetrate deeper into tissues and affect biological processes such as inflammation and energy production at a cellular level (read more below, in “How Red Light Therapy Works”)

What is Near-Infrared Light?

Near-infrared light is a small portion within infrared energy. It is the highest energy portion, (with middle-infrared and far-infrared having larger wavelengths and lower energy.)

Near-infrared light has a wavelength between 760 to 1400nm (1), with the most common wavelength used in commercial devices being around 810nm.

As mentioned above, near-infrared light therapy devices are used to penetrate deeper into tissues and affect biological processes such as inflammation and energy production at a cellular level (more on that below!) 

For the remainder of this article, I will use “infrared” interchangeably with “near-infrared.”

An illustrated diagram showing how red light versus infrared light can penetrate the skin and tissues to different depths

How Red Light Therapy Works

Both red light and near-infrared light can pass through soft and hard tissues and into the human body. They act at a cellular level to increase energy production and decrease oxidative stress. This improves tissue repair and decreases the body’s inflammatory response. (3)

Biological Mechanisms of Red Light Therapy

Red light therapy and infrared light therapy work in two places: on the skin’s surface level, and deeper at the cellular level to affect energy production and tissue repair. 

Red Light on the Skin Surface

What is the mechanism of red light therapy on the skin’s surface? 

Red light and infrared light cause low-level tissue damage to skin cells on the skin surface layer (the epidermis). This causes stem cells to be activated and recruited up to the skin’s surface for healing and tissue repair. 

This mechanism allows red light and infrared light to have beneficial effects on wrinkles, acne, scars, burns, and wound healing. (4)

A diagram showing how red light therapy acts on the skin surface to improve acne
Image source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126803/

Red Light at a Cellular Level

What is the mechanism of red light therapy at a cellular level?

Red light and infrared light can travel through the outer layer of the skin, and down deeper into tissues. The light energy enters into cells and the structures within cells, helping cells to produce more energy and to stop producing inflammatory molecules.

Inside your cells are certain molecules that are “light-sensitive.” This means that when they are exposed to certain wavelengths of light, they change shape or structure.

A figure showing how red light versus infrared light can penetrate soft tissue into the human body
Image source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126803/

One such molecule is called cytochrome c oxidase. This enzyme lives inside your mitochondria (remember, “the powerhouse of the cell”?) and is important in energy production for the cell. The cell’s energy source is called adenosine triphosphate (ATP). 

When your mitochondria are working efficiently, lots of ATP is produced, and your cells are using their energy supply to keep themselves healthy.When your mitochondria are NOT working efficiently, they can’t produce ATP very well, and they also produce more harmful molecules called reactive oxygen species. These reactive oxygen species cause oxidative stress inside the cell, leading to chronic inflammation. (5)

Too many reactive oxygen species can also affect gene expression in your cells – turning off genes that help the cell to grow and repair itself, and turning on genes that cause cell death. (4) (6)

Back to that enzyme, cytochrome C oxidase – it can be activated by certain wavelengths within red light and near-infrared light. These wavelengths of light “turn on” the enzyme, increase cellular energy production, and decrease the production of reactive oxygen species.

What’s more, increasing the mitochondrial activity in metabolically active tissues revs up your metabolism as a whole, and may have beneficial effects throughout your entire body, such as:

  • Increased cardiovascular performance and recovery from exercise (7).
  • Improved metabolism of glucose and fat, which may prevent diabetes, metabolic syndrome, obesity, and inflammation (8)
  • Possible better heart health and reduced risk of cardiovascular disease and hypertension (9) (These findings are mostly in rats, so human studies are still needed!)

To summarize, at a cellular level, red light and NIR light therapy improves the function of the mitochondria, blunts the inflammatory response, increases blood circulation, and increases the expression of genes involved in cell regeneration and tissue repair.

Put simply, when your cells’ mitochondria can create more energy and fewer inflammatory molecules, you will have fewer symptoms of aging and disease.

An infographic about red light versus infrared light

What are the Benefits of Red Light Therapy for Gut Health? 

To understand how red light therapy affects your gut health, you need some fundamental understanding of your gut microbiota, your circadian rhythms, and a little bit of how your cells work.

How does my gut microbiota affect my health?

From your skin surface to your mouth to the intestinal tract, the human body is teeming with microbes. Bacteria, viruses, fungi…but don’t run for the hand sanitizer! The vast majority of these microbes are not going to make you sick. On the contrary, a healthy population of microbes improves your health: strengthens the immune system, prevents illness, improves digestion and metabolism, and more.

The gut microbiota in particular is important for human health. 

From inflammatory bowel disease to diabetes to cardiovascular disease, a dysregulated gut microbiota is associated with increased risk of illness. Recent studies have even linked mental health disorders with the gut microbiota via the gut-brain connection. (10) 

People with gastrointestinal tract issues, such as irritable bowel syndrome, inflammatory bowel disease, or ulcerative colitis have imbalanced populations of gut bacteria; more “bad” species, and fewer “good” species. (11)(12)

One classic study was done in identical twins, where only one twin had Crohn’s disease. They analyzed the microbiota of both twins, and found very different populations of gut bacteria between the two. The twin with Crohn’s disease had way fewer species than the healthy twin. In the case of your gut bacteria, more diversity is typically better. (13)

A whole slew of factors can influence your gut microbiota: 

  • your family history
  • the foods you eat
  • Antibiotic use
  • alcohol consumption
  • your stress levels
  • even owning a pet!
  • (14)

Those who suffer from gut issues might have already tried probiotics or fiber-rich foods to improve their gut health. But recent studies are suggesting a new avenue for supporting the gut: red light therapy.

How do circadian rhythms affect my gut health?

Circadian rhythms in the human body are controlled mainly by light and dark. 

During daylight hours, bright light tells your body to turn on certain hormones, metabolic pathways, and brain circuits that support alertness, activity, feeding behavior, metabolism and more. 

Conversely, darkness turns those pathways off, while turning on others to support restfulness, repair, and healing (15)

The gut microbiota is circadian. What does this mean? It means the species of bacteria in your gut ebb and flow at different times of day, and with different foods you eat

So you can change your gut microbiota, your digestive health, and metabolic health with the power of circadian rhythms and light. (14)

Some simple examples of supporting your circadian rhythms might already sound familiar: going to bed at the same time each night, avoiding bright light before bed, and eating your meals around the same time each day.  Your body really likes predictability and patterns! (Read more here: How Stress Works (Part 1): Your Body’s Stress Response Pathway + How To Understand It)

Keep reading below for the mechanisms of how red light therapy benefits gut health.

How does red light therapy improve my gut health?

While recent studies are promising in showing that red light and near infrared light can improve gut health, it’s not completely understood how this works yet. 

Does red light get absorbed by your cells, and then downstream have beneficial effects on the gut microbiota? Or does red light get absorbed by the bacterial cells themselves? Is the circadian rhythm of gut populations responsible for the effect? Let’s talk through the possibilities.

A photo of a red light therapy device with text overlay says "red light and your mitochondria"

1. Improving gut health through cellular health + the mitochondria:

We know that red light and near-infrared light can enter into the cell and into mitochondria. 

The mitochondria is where the cell makes it energy (ATP) – but it’s also where inflammatory molecules (called reactive oxygen species) are created when the mitochondria are not working optimally.

Put simply, if you support the mitochondria to make more energy, and less reactive oxygen species, then you can reduce symptoms of aging and some diseases. 

So the question is – can red light enter into gut cells? Some recent research says yes!

One study suggests that red light can enter into gut neurons, supporting their mitochondria and activating the gut-brain connection via the vagus nerve. (16) (Read more about the vagus nerve here: (Vagus Nerve 101: How to Improve Vagal Tone for Better Gut, Heart, + Mental Health

This highway between the gut and the brain is important for proper digestion and metabolism, and for the health of the gut microbiota! (17) So, red light may improve mitochondrial health of neurons in the gut, activating the gut-brain axis which improves digestion, metabolism, and the health of your gut microbiota.

A graphic showing a person holding their belly with red light shining on it, overlaid with the title "Red light and the inflammatory response"

2. Improving gut health through reducing the inflammatory response:

In addition to reducing production of reactive oxygen species in the mitochondria, red light can also change the inflammatory response.

When the inflammatory response is already activated in cells, red light therapy can help reduce markers of inflammation. This is shown by:

  • Reduced pro-inflammatory cytokines (such as IL-6 and IL-8)
  • Reduced macrophages (immune cells that get recruited to sites of inflammation)
  • Reduced prostaglandins (6)

It’s important to note that these effects have been shown in tissues such as the brain, abdominal fat, skin, lungs, and spinal cord, but not necessarily in the gut. 

It could be inferred that these positive effects could happen in the gut as well, especially gut neuronal cells, but that research hasn’t directly been done yet! 

In the meantime, it doesn’t hurt to give red light therapy a try if you suffer from inflammatory bowel diseases, dysbiosis, and other disorders of gut health.

A photo of an alarm clock with a daytime background, and an alarm clock with a nighttime background, with a text overlay saying "Red light and your circadian rhythm"

3. Improving gut health through syncing circadian rhythms:

If you have a regular, synced circadian rhythm, your body knows what patterns to expect every day, because your sleep and eating behaviors are roughly the same every day.

A synced circadian rhythm means that the proper hormones and pathways are active in your body at the proper times. For example, digestive hormones and metabolic pathways are active during meal times, but not in the middle of the night. And conversely, hormones and neural pathways that support sleep are active during the night, and not during the day! (18) 

Red light therapy can be used to support circadian rhythms by avoiding bright light and instead using more dim red light lamps before bed. 

This isn’t a one-time fix; rather, it’s a habit that needs to be consistently practiced over time. This way, you can sync your circadian rhythm and support the hormones and biological pathways of your body. (19)

A photo of a red light therapy device overlaid with a graphic of the gut

How to Use Red Light Therapy for Better Gut Health

You might have skipped down to this section to get right to the tools you can use to improve your gut health using red light therapy. Those are coming! 

But in case you skimmed (or skipped ;)) the sections above, just know that this area of research is very new. The preliminary findings from animal studies are exciting and promising – red light therapy does seem to improve gut health! – but we still need human studies and clinical trials.

What red light therapy device should I use?

Many red light therapy devices are available on the market, so it’s helpful to know a few numbers and key terms to understand what is quality (and what is just a cheap, ineffective knockoff).

The wavelength of light that can travel deep through tissues to have effects on a cellular level is about 660nm to 850nm. 

This range includes red light AND near-infrared light, so if you can find a device with both, that is the best, because you will be taking advantage of all possible mechanisms.

It’s also a great idea to use an FDA-cleared medical grade device, as these have stricter standards safety, quality, and efficacy for medical use, as opposed to just aesthetic purposes.

How often should I use red light therapy?

You should use red light therapy every day for 10-15 minutes for several weeks to start seeing results. 

In most studies on red light therapy and gut health, this was the general protocol:

  • One session lasts 10-15 minutes
  • Red light therapy device held between 3 to 12 inches away from your body
  • At least 5 times a week
  • Continue this protocol for at least 2 – 8 weeks 
  • (20)(21)

What are the risks of red light therapy?

Please remember that this article is for informational purposes only and does not constitute medical advice. Please consult with a healthcare professional before starting any new treatment, including use of RLT. 

While the risks of red light therapy are low, you still need to use common sense. Don’t fall asleep with your light on, and don’t stare at a red light that is too intense or uncomfortable. Certain health conditions might preclude the use of red light therapy, including seizures or eye disorders or photosensitivity. 

Summary

Further research is still needed to uncover all the beneficial effects of red light therapy on gut health, but there are already promising results. Using red light may be able to support a healthy gut microbiome through cellular energy production, reduced inflammation, and modulating your circadian rhythms. 

In the future, human studies and clinical trials will be needed to dive further into the positive effect of red light and infrared light on your gut microbiota.

Let me know if you want to learn more about red light therapy and its effect on the brain, immune function, or other systems in the body!

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A graphic with an image of a red light therapy device and the title overlaid "Red Light Therapy Benefits"

References

References
  1. Butcher, G. (2016). The Electromagnetic Spectrum Video Series & Companion Book – Nasa Science. NASA. https://science.nasa.gov/ems/
  2. Schieke, S. M., et al. (2003). Cutaneous effects of infrared radiation: from clinical observations to molecular response mechanisms. Photodermatology, photoimmunology & photomedicine.
  3. Nizamutdinov, D. et al (2022). Transcranial near-infrared light in treatment of neurodegenerative diseases. Frontiers in Pharmacology
  4. Avci, P., et al. (2013, March). Low-level laser (light) therapy (LLLT) in skin: stimulating, healing, restoring. In Seminars in cutaneous medicine and surgery. NIH Public Access.
  5. Muñoz, A., & Costa, M. (2013). Nutritionally mediated oxidative stress and inflammation. Oxidative medicine and cellular longevity.
  6. Hamblin, M. R. (2017). Mechanisms and applications of the anti-inflammatory effects of photobiomodulation. AIMS biophysics.
  7. Ferraresi, C. et al. (2016). Photobiomodulation in human muscle tissue: an advantage in sports performance?. Journal of biophotonics.
  8. Hamblin, M. R. (2018). Mechanisms and mitochondrial redox signaling in photobiomodulation. Photochemistry and photobiology.
  9. Ad, N., & Oron, U. (2001). Impact of low level laser irradiation on infarct size in the rat following myocardial infarction. International journal of cardiology.
  10. Wang, B., et al. (2017). The human microbiota in health and disease. Engineering.
  11. Matsuoka, K., & Kanai, T. (2015). The gut microbiota and inflammatory bowel disease. In Seminars in immunopathology.
  12. Noor, S. O., et al. (2010). Ulcerative colitis and irritable bowel patients exhibit distinct abnormalities of the gut microbiota. BMC gastroenterology.
  13. Dicksved, J. et al. (2008). Molecular analysis of the gut microbiota of identical twins with Crohn’s disease. The ISME journal
  14. Liang, X., & FitzGerald, G. A. (2017). Timing the microbes: the circadian rhythm of the gut microbiome. Journal of biological rhythms.
  15. Potter, G. D. et al. (2016). Circadian rhythm and sleep disruption: causes, metabolic consequences, and countermeasures. Endocrine reviews.
  16. Liebert, A. et al. (2019). “Photobiomics”: can light, including photobiomodulation, alter the microbiome?. Photobiomodulation, photomedicine, and laser surgery.
  17. Cryan, J. F., et al. (2019). The microbiota-gut-brain axis. Physiological reviews.
  18. Leone, V. et al. (2015). Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism. Cell host & microbe.
  19. Tähkämö, L. et al. (2019). Systematic review of light exposure impact on human circadian rhythm. Chronobiology international.
  20. Chen, Q. et al. (2021). Gut flora-targeted photobiomodulation therapy improves dementia in an Aß-induced Alzheimer’s disease animal model. Journal of Photochemistry and Photobiology B: Biology.
  21. Bicknell, B. et al. (2019). Photobiomodulation of the microbiome: implications for metabolic and inflammatory diseases. Lasers in medical science.

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Gratitude + Your Gut: 6 Health-Boosting Tips You Need to Know https://rvy.ayu.mybluehost.me/how-gratitude-improves-your-gut-health/?utm_source=rss&utm_medium=rss&utm_campaign=how-gratitude-improves-your-gut-health https://rvy.ayu.mybluehost.me/how-gratitude-improves-your-gut-health/#respond Tue, 02 Jan 2024 17:17:15 +0000 https://rvy.ayu.mybluehost.me/?p=1320 You might already know that practicing gratitude is good for your mental health – but did you know gratitude improves gut health, facilitates better digestion, optimizes gut bacteria populations, and improves metabolism? Read on to learn 6 ways you can use gratitude to boost your gut health every day. Signs of emotional eating or stress...

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You might already know that practicing gratitude is good for your mental health – but did you know gratitude improves gut health, facilitates better digestion, optimizes gut bacteria populations, and improves metabolism? Read on to learn 6 ways you can use gratitude to boost your gut health every day.

Signs of emotional eating or stress eating 

Do any of these sound like you?

  • I eat when I am emotional or stressed out 
  • I see food as black and white – sometimes as a reward, sometimes as a temptation
  • I often have food cravings or use snacks as a pick-me-up
  • I have stomach discomfort, gas, bloating, and/or excessive fullness after meals
  • I feel out of touch with my body
A woman with her hands clasped in front of her in prayer

If you said “yes” to any of these, you might benefit from learning about how gratitude improves gut health through mindfulness around eating!

(Read more about stress here: Stress Less: 5 unique steps to banish stress + feel better)

How emotional eating affects your digestion

When you eat from an emotional, stressed, or out-of-touch state, it wires your brain to be in a fight-or-flight state during meals. Fight-or-flight means your sympathetic nervous system is activated. This moves blood flow AWAY from your digestive tract, reducing the release of hormones and secretions needed for digestion. (1) 

The result? Your body doesn’t have the materials it needs to digest properly, and you feel dissatisfied and uncomfortable after eating.

Keep reading to learn how to improve gut health using gratitude, and the neuroendocrine mechanisms that make it happen.

How does gratitude improve digestion?

Woman Smelling the Food

Even before you take a bite of a meal, digestion begins with the brain! 

When you smell food, look at food, or even think about food it triggers the release of hormones, peptides, and substances that start the digestive system churning. (2) 

This is a good thing! Essentially, it’s priming the pump so that your body is in the right state to digest and metabolize your food efficiently.

This ‘prime the pump’ effect works better when you approach your meal with gratitude, calm, and mindfulness – rather than distraction, stress, or self-loathing.

These emotions can activate your sympathetic nervous system (as mentioned above). So before you eat, it helps to get your mind into a calm, relaxed, grateful state first.

What hormones does gratitude release?

To get your digestive system running like a well-oiled machine, you need the proper release of hormones and digestive juices (ugh, I know, gross-sounding – but true).

Here are just a few of the digestive all-stars, (hormones and more) that are released when you’re getting ready to eat:

Ghrelin:

  • The hormone responsible for tummy rumbling, also known as peristalsis.
  • Ghrelin kinda sounds like “growlin’”, so that’s how you can remember it!
  • When you smell and see food, your stomach releases ghrelin. Ghrelin then signals to your brain (via the vagus nerve) and tells it to start making hormones to increase your appetite. And it signals your stomach to start churning. Cue the stomach growls!  (3).   

Salivary amylase:

  • A fancy name for the digestive enzyme in your spit.
  • Amylase is an enzyme that munches up starchy foods. You can help this enzyme do its work by chewing your food really well – think: applesauce consistency.  (4).
  • Chewing really well means your intestinal enzymes don’t have to work as hard – which translates to less digestive discomfort and bloating for you!

Gastrin and Hydrochlroic acid:

  • Stomach acid – you need enough of this stuff to break down food, especially protein.
  • Again, the sights, smells, and first bites of food are your friend here; they all help start the digestive chain of events. These sensory cues cause a hormone called gastrin to be produced, and gastrin is what tells your stomach to produce its acid. (5).
  • Eating mindlessly and under stressful conditions can prevent sufficient gastrin and stomach acid production! (e.g., have you ever scarfed a breakfast burrito in one hand while commuting to work and then had heartburn all morning? No, just me?)

So do your hormones and stomach acid a favor and get into a grateful, present state before eating, and let gratitude do its work to improve your gut health.

A picture of an anatomy model of a brain

Gratitude improves gut health through the gut-brain axis

Studies are increasingly showing the benefits of mindfulness and gratitude on the gut microbiome. Not all types of gut bacteria are created equal – there are good bugs (beneficial species), and bad bugs (pathogenic species). Research has found that those with depression, and anxiety have less of the beneficial species, and more of the pathogenic species. (6, 7)

While science hasn’t quite found a supplement you can take to fix this, there’s an even easier method you can try. Gratitude and mindfulness approaches, like meditation and prayer, have been shown to tip this balance, lessening the bad bugs and increasing the good bugs! (8)

*This is NOT to say that you can think your way out of depression or anxiety. I am all for a multi-pronged approach to these mental disorders. This includes both conventional medicine AND functional and integrative therapies. In fact, having suffered from postpartum depression and anxiety myself, I am very grateful for SSRIs and talk therapy. 

Nonetheless, I am also a big fan of integrating ALL of the resources available to me to tackle my health struggles, from conventional Western to alternative and complementary therapies. Since gratitude is such a simple practice that we can all do, and the benefits are increasingly supported by research, why not try it?

How does gratitude improve metabolism?

Neuroscience studies show us that stress causes a fight-or-flight response, in which hormones such as cortisol and epinephrine are released.

These stress hormones prevent blood flow to the gut, and block digestive hormones, enzymes, and secretions from being released (9).

They also prevent proper uptake of blood glucose, which sends you on a roller coaster of glucose and insulin spikes, energy crashes and fatigue, and sugar cravings. and inflammation. (10) Proper control of blood glucose – not too high, not too low – is essential for a stable mood, clear mind, and sustained energy. (11) 

Conversely, when you are in a relaxed, mindful, and grateful state, your digestion and metabolism can run more smoothly.

Properly digested food feeds the beneficial bacteria in your gut. These good bugs munch up the food that reaches your large intestine, and they especially love *fiber.* They metabolize the fiber, then release short-chain fatty acids.

Short-chain fatty acids give you all kinds of metabolic benefits, from preventing inflammation, to reducing your risk of obesity and diabetes, to maintaining a healthy and strong gut barrier. (12, 13). This just another way that gratitude improves gut health.

Can gratitude help you lose weight?

While weight loss is not necessarily a bad goal, it is often equated with being healthy. This is a problem, because losing weight is a complex process and health is much more than a number on a scale! 

Health includes nutritional nourishment, vibrant energy, quality sleep, nurtured relationships, and stable mental health. People strive for weight loss for a variety of reasons, but to make it sustainable, it should be attempted alongside the goal of improving health holistically. (14)

With that in mind, there is science showing how gratitude improves body image satisfaction. Since positive body image is shown to increase healthy lifestyle choices, this can support your weight loss goals. (15, 16) 

In one study, researchers had the subjects fill out a self-evaluation on body image and health behaviors. (15) One group was a control group, and the other was a “gratitude” group that did a gratitude journaling exercise prior to the evaluation. Here is the prompt that the researchers used for the gratitude group:

Think about aspects of your body that you are grateful for. This can be anything, including your health, physical appearance, or the functionality of your body. Try to come up with at least five things. Take a minute and really think about those things, picturing them in your mind. Once you have finished thinking about these things, choose at least three of them and write about why you are grateful for those things.” (15)

Dunaev, J, et al. “An attitude of gratitude: The effects of body-focused gratitude on weight bias internalization and body image.”

The gratitude group showed significantly lower internalized weight bias and significantly greater body satisfaction. These findings are encouraging and can be integrated by anyone attempting to lose weight in a healthy, holistic, sustainable way. 


6 Ways to Cultivate Gratitude for Gut Health

Here are 6 practical tips to cultivate gratitude, improving gut health, digestion, and metabolism!

1. Verbally express gratitude before eating

  • Before eating, take a moment to notice how grateful you are for the food in front of you! It can help to express your thankfulness out loud before eating – you can do this through prayer, or even just a simple statement like, “I am thankful for the gift of this meal, and all the people who worked to bring it to my table.”

2. Take your time when eating

  • You can help your body do its digestion thang by slowing down! Set your fork down between bites, take deep breaths and try to allow your body to relax. This helps you notice your body’s hunger and fullness cues, and keeps you into a state of gratitude and receiving. It also helps if you eat with family members or friends – social connection increases satisfaction and helps you slow down! (17)

3. Remove distractions and be mindful at mealtime

  • No distractions. You can best notice, savor, and feel thankful for your food when you’re not mindlessly scrolling while simultaneously shoveling (don’t worry, I do it too). Plus, the dopamine storm that you unleash when you constantly look at your phone really hampers your digestive processes. (18). Help re-wire your brain circuitry by setting your phone aside during meals, and over time, it will become easier to be more mindful and present while you eat. Your gut will thank you!

4. Chew your food all the way

  • Try chewing your food completely, no wolfing! Think of chewing your food til it’s the consistency of applesauce. While you chew, notice and appreciate the flavors and textures. This will increase your satisfaction and fullness after the meal. It will also increase the necessary digestive enzymes and hormones needed to digest and metabolize your food properly, which is great for preventing bloating, discomfort, and blood sugar imbalances. (19)

5. Try gratitude journaling

  • Neuroscience and psychology research shows that writing down things you’re grateful for increases satisfaction, improves body image, and reduces stress, which are all beneficial for an optimally-functioning metabolism (15, 20). You can do this before mealtime, or any other time of day and still get the same benefits!

6. After eating, sit for 5 minutes

  • Sit for 5 minutes and appreciate your meal and notice how your body feels. It can take about 20 minutes for your brain to register your fullness cues (21), so planning to sit and luxuriate in your meal after eating is a great way to let your brain catch up with the rest of your body!

Thanks for reading along and learning how gratitude improves your gut health, digestion, and metabolism. For more science-backed, functional health content, keep exploring the blog, and join the Granola Science email list!

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References part 1
  1. Lomax, AE  et al., The Innervation of the Gastrointestinal tract. Yamada’ s Textbook of Gastroenterology. 2015. https://doi.org/10.1002/9781118512074.ch15
  2. Browning, K. N., & Travagli, R. A. (2014). Central nervous system control of gastrointestinal motility and secretion and modulation of gastrointestinal functions. Comprehensive Physiology, 4(4), 1339–1368. https://doi.org/10.1002/cphy.c130055
  3. Nunez-Salces M, Li H, Feinle-Bisset C, Young RL, Page AJ. The regulation of gastric ghrelin secretion. Acta Physiol. 2021; 231:e13588. https://doi.org/10.1111/apha.13588
  4. Freitas, D. et al., The important role of salivary α-amylase in the gastric digestion of wheat bread starch. Food Funct. 2018. DOI: 10.1039/C7FO01484H
  5. Schubert, ML., Peura, DA. Control of Gastric Acid Secretion in Health and Disease. Gastroenterology. 2008. https://doi.org/10.1053/j.gastro.2008.05.021
  6. Dinan TG, Cryan JF. Brain-Gut-Microbiota Axis and Mental Health. Psychosom Med. 2017. doi: 10.1097/PSY.0000000000000519.
  7. Kouraki A, et al., Reproducible microbiome composition signatures of anxiety and depressive symptoms. Comput Struct Biotechnol J. 2023 doi: 10.1016/j.csbj.2023.10.035.
  8. Househam, AM et al., “The effects of stress and meditation on the immune system, human microbiota, and epigenetics.” Adv Mind Body Med. (2017). https://choprafoundation.org/wp-content/uploads/2023/03/The_Effects_of_Stress_and_Meditation_on.pdf
  9. Browning, K. N., & Travagli, R. A. (2014). Central nervous system control of gastrointestinal motility and secretion and modulation of gastrointestinal functions. Comprehensive Physiology, 4(4), 1339–1368. https://doi.org/10.1002/cphy.c130055
  10. Joana Araújo et al., “Prevalence of optimal metabolic health in American adults: National Health and Nutrition Examination Survey 2009–2016,” Metabolic syndrome and related disorders 17, no. 1 (2019): 46-52, https://pubmed.ncbi.nlm.nih.gov/30484738/.
  11. Guido Freckmann et al., “Continuous glucose profiles in healthy subjects under everyday life conditions and after different meals,” Journal of diabetes science and technology 1, no. 5 (2007): 695-703, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/
References part 2

12. Xiong RG et al. Health Benefits and Side Effects of Short-Chain Fatty Acids. Foods. 2022. doi: 10.3390/foods11182863.

13. Maltz, Ross M., et al. “Social stress affects colonic inflammation, the gut microbiome, and short chain fatty acid levels and receptors.” Journal of pediatric gastroenterology and nutrition 68.4 (2019): 533

14. Benton, D., & Young, H. A. (2017). Reducing Calorie Intake May Not Help You Lose Body Weight. Perspectives on psychological science : a journal of the Association for Psychological Science, 12(5), 703–714. https://doi.org/10.1177/1745691617690878

15. Dunaev, J, et al. “An attitude of gratitude: The effects of body-focused gratitude on weight bias internalization and body image.” Body image. 2018. https://doi.org/10.1016/j.bodyim.2018.01.006

16. Bouzas C et al. Relationship between Body Image and Body Weight Control in ≥55-Year-Old Adults: A Systematic Review. Int J Environ Res Public Health. 2019. doi: 10.3390/ijerph16091622

17. Dunbar RIM. Breaking Bread: the Functions of Social Eating. Adapt Human Behav Physiol. 2017. doi: 10.1007/s40750-017-0061-4.

18. Cherpak CE. Mindful Eating: A Review Of How The Stress-Digestion-Mindfulness Triad May Modulate And Improve Gastrointestinal And Digestive Function. Integr Med. 2019 Aug https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219460/

19. Miquel-Kergoat, Sophie, et al. “Effects of chewing on appetite, food intake and gut hormones: a systematic review and meta-analysis.” Physiology & behavior 151 (2015): 88-96.

20. O’Connell BH, Killeen-Byrt M. Psychosocial health mediates the gratitude-physical health link. Psychol Health Med. 2018 doi: 10.1080/13548506.2018.1469782

21. Blackburn, KB. What happens when you overeat? MD Anderson Cancer Center. 2018. https://www.mdanderson.org/publications.html

Granola Science posts referenced in this post:

Stress Less: 4 strategies to banish stress + feel better

Vagus Nerve 101: How to Improve Vagal Tone for Better Gut, Heart, + Mental Health

Disclaimer: No content on this site should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

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Vagus Nerve 101: How to Improve Vagal Tone for Better Gut, Heart, + Mental Health https://rvy.ayu.mybluehost.me/vagus-nerve-function-101/?utm_source=rss&utm_medium=rss&utm_campaign=vagus-nerve-function-101 https://rvy.ayu.mybluehost.me/vagus-nerve-function-101/#respond Mon, 01 Jan 2024 18:35:54 +0000 https://rvy.ayu.mybluehost.me/?p=1373 Learn how the vagus nerve functions on the heart, gut, breath, and mind. Read on for the benefits of optimizing your vagus nerve and how to improve your vagal tone to balance your nervous system, reduce stress, and get into a healing state.

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This post is all about vagus nerve function on the heart, gut, breathing, and mind. Read on for the benefits of optimizing your vagus nerve and how to improve your vagal tone to balance your nervous system, reduce stress, and get into a healing state. 

What is the main vagus nerve function and why is it important?

Say hello to the body’s “wandering nerve.” The vagus nerve is the main nerve of the parasympathetic nervous system, traveling from your brainstem to the depths of your abdomen. The vagus nerve function includes everything from your heartbeat to your digestion, mood and immunity. Learn how to utilize the vagus nerve to get your body into a state of calm, safety, and healing!

A two-way highway

The vagus nerve is a neural pathway that communicates brain to body, and body to brain. It helps connect your brain and your internal organs, regulating things like digestion, heart rate, breathing, and immune system, as well as our emotions related to each of these bodily functions. (1) 

Why is it important to understand the vagus nerve function for overall health?

Understanding the vagus nerve can help you understand your brain-body connection, and help you better control your body’s nervous system, whether you are in a sympathetic state (fight-or-flight) or a parasympathetic state (rest-and-digest). 

Both of these states are important and necessary! But in our modern lives, we tend to exist in a sympathetic state more often than not. 

Because our brain doesn’t differentiate between real stress (e.g., a saber tooth tiger chasing you), and perceived stress (e.g., sitting in rush hour traffic), many people tend to be in a chronic fight-or-flight state, much to the detriment of our gut health, heart health, and mental health.

Taking control of your vagus nerve can help you manage the state of your nervous system and better nurture these body systems. This can improve digestion, metabolism, heart function, breathing, stress, and anxiety. In other words, the vagus nerve is a big part of sensing and controlling our internal self.

Understanding the vagus nerve: anatomy and physiology

Vagus nerve anatomy: Where is it located?

The vagus nerve is the 10th cranial nerve, with its neurons extending from the brainstem and down through the neck into the various organs in the abdomen, including the heart, lungs, and digestive tract. (2)

Why is it called the wandering nerve?

The vagus nerve is nicknamed “the wandering nerve” because it is the longest nerve in the body. ‘Vagus’ in Latin means  “straying” or “wandering.” 

So the vagus nerve “wanders” along a branching path, from your brain stem to internal organs such as your heart, lungs, and gut. (1)

Source: https://www.womenshealthnetwork.com/heart-health/vagus-nerve-deep-breathing-benefits/

What is the vagus nerve function within the parasympathetic nervous system?

The vagus nerve is the main nerve of the parasympathetic nervous system. The vagus nerve functions as a two-way highway, with two main directions: up and down. Some branches go “up” (from internal organs up to the brain), while others go “down” (from the brain down to various organs and body systems: stomach, intestines, heart, lungs, the immune system, etc.) 

The “up” pathway:

The vagus nerve network sends sensory information from all of these organs and systems up to the brain, giving our brain information. And then our brain decides how to feel about that sensory information! For example:

  • How full or hungry you are
  • How fast your heart is beating
  • How fast or slow you are breathing
  • Whether your immune system is fighting an infection
  • Emotions toward all of these sensations
  • (2)

The “down” pathway

In the other direction, the vagus nerve sends motor control impulses from your brain down to these organs and systems. These impulses are mostly autonomic, i.e., not under our voluntary control. (2)

That being said, there are still ways to influence this pathway to gain better control over your brain-body connection and improve your mood and well being!

A woman standing in front of the ocean looking up

Functions of the vagus nerve

Heart: What is the vagus nerve’s function on the heart?

  • Slows the heart rate
  • Reduces the contractility (or the forcefulness) of each heart beat
  • Reduces blood pressure by dilating blood vessels
  • Vagus nerve stimulation could be used as a potential therapy to prevent heart attack, stroke, and other cardiovascular complications.
  • (6)

Gut: What is the vagus nerve’s function on digestion and gut health?

  • Causes the stomach to contract (“peristalsis”), This helps digest food and move it along the digestive tract 
  • Causes the stomach to release stomach acid and other digestive secretions, helping digest food
  • Causes the liver to release bile, which is essential for digesting fat, and also important for your body’s detoxification and waste removal pathways (Read more about Bile and Detox):
  • Causes your small intestine to contract (more peristalsis, woohoo!), as well as digestive enzymes to be released from your pancreas into your small intestine.
  • (5)

Mental Health: What is the vagus nerve’s function on stress, anxiety, and mood?

The vagus nerve is like a two-way highway that communicates between organs and the brain’s centers of emotion regulation. This cross-talk explains how stress, feelings, and thoughts can influence the function of your gut, heart, breathing, etc. (and vice versa). Your body’s sensations significantly contribute to your emotional regulation!

  • If your heart rate is high, blood pressure is high, breathing is quick, etc., the vagus nerve pathway communicates anxiety, fear, and stress to your brain.
  • Conversely, if heart rate is slow, breathing is calm, your stomach is comfortably full, etc., the vagus nerve pathway communicates safety, calm, and healing to your brain.
  • (5)

(Read more about your body’s stress response pathway here: Stress Less: 4 strategies to banish stress + feel better)

What happens when the vagus nerve is overstimulated?

You have to be more specific than just saying “stimulating” the vagus nerve. Because it participates in so many different body functions, some pathways and circuits of the vagus nerve are more desirable than others for general well-being. (For example, the vagus nerve can mediate a slower heart rate and calmer breathing…but it also is the mediator of nausea and a fever when your immune system is fighting an infection!)

In general, the vagus nerve mediates actions that are a part of the parasympathetic nervous system. So, a healthy vagus nerve can allow your nervous system to move smoothly in between a sympathetic state and a parasympathetic state. Both states are necessary!

  • A sympathetic, or “fight-or-flight,” state is important for alertness and activities like exercise, working with deadlines, or quick response to emergencies. 
  • A parasympathetic state, or “rest-and-digest” is important for autonomic processes like heart rate, blood pressure, digestion, urination, and sweating. 
  • (7)

When we talk about stimulating the vagus nerve, we are wanting to stimulate the vagal circuits that will benefit health: e.g., ease anxiety, promote digestion, breath calmly and slowly, and be mindful of our internal sensations. (2). See below, “Ways to Stimulate and Support the Vagus Nerve” for techniques on how to do this!

What is vagal toning?

Vagal tone describes how much your parasympathetic nervous system is activated.

Vagal tone is measured indirectly using heart rate variability (HRV), which is the change in the time interval between successive heartbeats. (3). Low vagal tone, as measured using HRV, is associated with digestive disorders like IBS, cardiovascular conditions, poor resilience to stress, and inflammation. (4), (5)

What are the symptoms of an irritated vagus nerve? What are the symptoms of a vagus nerve shutdown?

As mentioned above, a low HRV indicates low vagal tone. This may mean you are often in a sympathetic (fight-flight-freeze) state, or don’t have a strong connection between brain and body.

Additionally, here are some more indicators that you may have low vagal tone, or a disconnect between body and brain:

  • Impaired digestion
  • Bloating or discomfort after eating
  • Easily overstimulated (hi, moms everywhere!)
  • Hard to get out of bed in the morning
  • Can’t hold still, fidgeting, or jiggling
  • Feeling spacey, dizzy, or out-of-touch with your body
  • Chronic stress. Stress shuts down the connection between the gut and the brain.

Signs you may have poor vagal tone:

Your regular, daily habits are the most important factor for healthy vagus nerve function, and a strong connection between your brain and body. These are a few things that can contribute to poor vagal tone:

  • Skipping breakfast
  • Not enough protein
  • Poor relationships, or isolation from friends and family
  • Overusing social media (especially at night before bed)
  • Zoning out or numbing (e.g., constant scrolling, mindless eating, or marathoning Netflix) 
  • Rushing through meals or being distracted during meals
  • Blood sugar roller coasters – remember, both high and low blood sugar are stressors! So don’t wait until you’re absolutely starving to eat, and try to pair fiber or protein with carbohydrates.

Benefits of optimizing vagus nerve function

What are the benefits of strengthening the vagus nerve?

  • Improved mental health, emotional well-being, and stress resilience.
    • Anxiety and low mood are associated with poor gut health, which can lead to things like high inflammatory markers, and decreased serotonin and other mood-enhancing neurotransmitters. (5) In addition, low vagal tone indicates your body is often in a fight-or-flight mode, meaning high stress hormones like cortisol and epinephrine. Improving vagus nerve function helps combat this.
  • Better digestion and gut health
    • Stress shuts down the connection between the gut and the brain via the vagus nerve. This leads to poor digestion, bloating, feeling tired or sick after eating.  (2). 
    • Be mindful of the state you’re eating in! Being in a fight-or-flight state with high cortisol impedes digestion and nutrient absorption. You can eat a balanced, nutritious meal and STILL feel bloated, tired, or unsatisfied afterward if you are not in a calm, mindful, parasympathetic state. Try unplugging and taking a few deep breaths before your meal. (2) (Read more: How gratitude heals your gut: 6 health-boosting tips you need to know).
  • Heart health
    • Healthy vagus nerve function is associated with a lower resting heart rate, lower blood pressure, and decreased markers of inflammation (5).
Paperclip in a Shape of a Light Bulb and a Rubber Eraser in a Shape of a Brain

Ways to Stimulate and Support the Vagus Nerve

Do vagus nerve exercises actually work?

Yes! For decades, clinical research has been conducted on vagus nerve stimulation devices. They usually hook onto the outer ear and deliver electrical pulses to stimulate the vagus nerve. These devices have been shown to help treat epilepsy, depression, migraines, obesity, and even dementia and Alzheimer’s. (8)

More current research is showing that less invasive techniques are similarly effective at stimulating the same pathways to improve vagus nerve function. For example, auricular massage (ear massage), deep breathing exercises, meditation, humming, and cold plunges. (9) (Read more: How to cold plunge safely – for healthy weight and less stress)

How to use meditation to strengthen vagal tone 

Meditation is so powerful! And you can make it very simple. Try this simple prompt to support vagus nerve function:

  • First, close your eyes. Pay attention to your heartbeat and your breathing. 
  • Notice if your heartbeat is fast or slow. 
  • Count your heartbeats without placing your finger on your pulse in your wrist or neck. 
  • Notice if your breathing is deep or shallow, if it’s longer on the inhale or longer on the exhale.
  • Get to know these internal body signs, and you will strengthen your vagus nerve, your connection between your body and your brain, your ability to focus, and even your ability to relate to and empathize with other people around you.
  • (10)

Nutrition and its role in vagus nerve health

You might ask what foods can heal the vagus nerve? Here are a few key nutrients that are essential for proper functioning of the vagus nerve:

  • Fiber for a healthy gut that moves well, 
  • B-vitamins for proper energy metabolism and methylation (involved in detoxification) pathways. 
  • Probiotic-rich foods for maintaining a healthy gut microbiome. 
  • (2)
  • In addition, here are some food sources of the above nutrients:
    • Fiber = avocados, sweet potatoes, cooked veggies. (These are all gentle sources of fiber that make your gut microbiome happy with less chance of digestive discomfort.)
    • B-vitamins = salmon and other fish, red meat, eggs, chickpeas and other legumes, sunflower seeds, and liver! 
    • Probiotic-rich food = fermented foods with live cultures such as yogurt, kefir, sauerkraut, kimchi, or kombucha. 

Social connections and positive relationships

Increasing the connectivity and functioning of your vagus nerve has positive effects on social connections and relationships. Your brain can literally be more attuned to others emotions and stress levels when you have a strong vagal tone. (10)

Incorporating vagus nerve-friendly activities into daily life

Just sprinkling in vagus-nerve-friendly exercises here and there can have a positive effect.

As often as you remember, try to pause whatever you’re doing whether it’s writing an email or washing the dishes, and take a mindful moment. Just close your eyes for a few moments and practice some meditative noticing. You can try the meditation prompt above, or make it even shorter and simpler. Count to your heartbeats, notice your breathing, or try humming to yourself. It doesn’t have to be a full-on meditation; just the simple act of tuning into your body’s internal environment is shown to have benefits for vagal tone. You can do this just two or three times a week and still gain benefits to your vagus nerve! (10)

Grounding

Grounding is walking or standing outside while barefoot. The negative ions from being outside reduce cortisol, increase serotonin, increase immune function, and decrease depression/seasonal affective disorder, anxiety, and sleep disorders. (11). 

Negative ions are naturally occurring molecules that have a negative electrical charge. They are found in the atmosphere, and released from bodies of water like lakes, rivers, and the ocean.  (12)

Summary

The vagus nerve is a two-way communication highway between the brain and various internal organs: heart, gut, lungs, etc. It is the main nerve network of the parasympathetic nervous system, aka the rest-and-digest system. 

Above all, healthy functioning vagus nerve, or vagal tone, means that you have a healthy brain-body connection. This benefits your gut health, heart health, and mental health!

Vagal tone is measured by heart-rate variability (HRV) – with a higher HRV indicating a better vagal tone. 

You can optimize your vagus nerve by practicing mindfulness, meditation, grounding, prioritizing social connections, and eating foods that support a healthy gut (such as fiber, B-vitamins, and probiotic-rich foods). Certain vagus nerve exercises such as humming, breathwork, cold plunges, and auricular (ear) massage have been shown to stimulate the vagus nerve as well. 

Which one of these techniques do you want to try? What other vagus nerve tips and tricks have you incorporated into your life? Let me know in the comments!


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Granola Science posts referenced:

How gratitude heals your gut: 6 health-boosting tips you need to know

Stress Less: 4 strategies to banish stress + feel better

References
  1. Dolphin H. et al., “The Wandering Nerve Linking Heart and Mind” – The Complementary Role of Transcutaneous Vagus Nerve Stimulation in Modulating Neuro-Cardiovascular and Cognitive Performance.” Front. Neurosci., 2022 Sec. Autonomic Neuroscience. DOI: https://doi.org/10.3389/fnins.2022.897303.
  2. Humberman, A. (Host) (2021 – present). How Foods and Nutrients Control Our Moods. Huberman Lab Podcast. https://www.hubermanlab.com/episode/how-foods-and-nutrients-control-our-moods?timestamp=750.
  3. Laborde, S. et al., Heart Rate Variability and Cardiac Vagal Tone in Psychophysiological Research – Recommendations for Experiment Planning, Data Analysis, and Data Reporting. Front Psychol. 2017. DOI: 10.3389/fpsyg.2017.00213
  4. Weber, C.S., Thayer, J.F., Rudat, M. et al. Low vagal tone is associated with impaired post stress recovery of cardiovascular, endocrine, and immune markers. Eur J Appl Physiol. (2010). https://doi.org/10.1007/s00421-009-1341-x
  5. Bonaz B. et al., Vagal tone: effects on sensitivity, motility, and inflammation. 2016. Neurogastroenterology & Motility. DOI: https://doi.org/10.1111/nmo.12817 
  6. Capilupi, M. J., et al. (2020). Vagus nerve stimulation and the cardiovascular system. Cold Spring Harbor perspectives in medicine. doi: 10.1101/cshperspect.a034173
  7. Cleveland Clinic. (2022, June). Parasympathetic Nervous System (PSNS). Cleveland Clinic. https://my.clevelandclinic.org/health/body/23266-parasympathetic-nervous-system-psns.
  8. Goggins, E., et al. (2022). Clinical perspectives on vagus nerve stimulation: present and future. Clinical Science (London, England : 1979), 136(9), 695–709. https://doi-org.uws.idm.oclc.org/10.1042/CS20210507.
  9. Gerritsen, R. J., & Band, G. P. (2018). Breath of life: the respiratory vagal stimulation model of contemplative activity. Frontiers in human neuroscience, 397
  10.  Humberman, A. (Host) (2021 – present). How to Optimize Your Brain-Body Function & Health. Huberman Lab Podcast. https://www.hubermanlab.com/episode/how-to-optimize-your-brain-body-function-and-health?timestamp=5933.
  11. Chevalier, G., & Sinatra, S. T. (2011). Emotional stress, heart rate variability, grounding, and improved autonomic tone: clinical applications. Integrative Medicine, 10(3), 16-21
  12. Jiang, S. Y., et al. (2018). Negative air ions and their effects on human health and air quality improvement. International journal of molecular sciences, 19(10), 2966.

No content on this site should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician.

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What does “crunchy living” mean? 4 simple reasons you might want to try it! https://rvy.ayu.mybluehost.me/what-is-crunchy-living/?utm_source=rss&utm_medium=rss&utm_campaign=what-is-crunchy-living https://rvy.ayu.mybluehost.me/what-is-crunchy-living/#respond Mon, 18 Dec 2023 18:07:35 +0000 https://startertemplatecloud.com/g50/?p=156 You may have heard of the term “crunchy living” or “granola girl.” But what does it actually mean to be crunchy? Although some people think crunchy living is just a cute aesthetic on Pinterest with plaid flannels and boots from REI, or a weirdly aggressive crunchy mom on TikTok who will judge you if you...

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You may have heard of the term “crunchy living” or “granola girl.” But what does it actually mean to be crunchy?

Although some people think crunchy living is just a cute aesthetic on Pinterest with plaid flannels and boots from REI, or a weirdly aggressive crunchy mom on TikTok who will judge you if you don’t cloth-diaper your infant, being crunchy is certainly not a one-size-fits-all lifestyle – it’s a spectrum of choices that all focus on improving health! You can make intentional choices to benefit your health and your family’s health in a way that works for you.

Read on to learn how to live more crunchy, as well as reasons why you might want to.

Crunchy lifestyle meaning

Living crunchy is seeing that all your body’s systems are interconnected with each other, as well as with your spiritual, social, and mental health. You approach your health and lifestyle choices from this holistic, integrated perspective.

Our health and lifespan are affected by factors that are sometimes out of our control, like genetics, socioeconomic status, and early development.

A woman holding a pomegranate that is cut in half

However, there are many things we can control, like our environmental influences and behavioral habits such as nutrition, movement, and emotional self-care. (1)

Moreover, people who proactively engage in alternative and holistic health practices tend to have better health and live longer (2).

So, you might be crunchy if you grow your own vegetables, have made your own DIY bug spray, prioritize buying products that are sustainable or less toxic, or have something fermenting on your kitchen counter right now. Even if you’ve never done one of these specifically, there are so many different ways to practice crunchy living.

Growing popularity of crunchy living

In the past several years, the crunchy movement has taken the world (i.e., the internet) by storm (3, 4). It has become popular to live a lifestyle focused on slowing down, prioritizing health, and listening to your body. Which is fantastic! Since more and more people are working from home, pursuits that were once thought of as hippie or earthy, such as baking sourdough bread, gardening, and homesteading, have become more mainstream (5).

As “crunchy” becomes more mainstream, I’d like to point out that being crunchy is a buffet of choices. So you can pick and choose what works best for you and your family! Maybe you want to prioritize adding more probiotic-rich foods to your diet, but you don’t want to start churning your own butter or making your own laundry detergent. You might love herbs and home remedies, but you also embrace modern medicine. That’s great!

Above all, take what resonates with you, leave the rest, and don’t let it stress you out (the health implications of stress are a whole ‘nother rabbit hole you can go down).

Living a crunchy lifestyle is a privilege

It’s especially important to point out that living a crunchy lifestyle is a privilege. It is a privilege to have the time, space, financial means, and support to pursue this style of living — for example, to be able to bake your own bread from scratch, shop organic, buy more sustainable (and more expensive) household products, or even choose to breastfeed. (6)

These, of course, are just a few choices that people make when pursuing a more natural lifestyle, and you don’t have to do any or all of those to call yourself crunchy! But I would be remiss if I did not acknowledge the privilege it is to be able to pursue this type of lifestyle. It’s important to practice gratitude to have the means to pursue this kind of lifestyle (and hey, you can get all the health benefits of practicing gratitude while you’re at it!)

Exploring the benefits of crunchy living

Why would you want to try and live a more crunchy lifestyle? Living more naturally and focusing on health has many benefits – in fact, there are too many to list here! Consider this a starting point, and add your own crunchy living methods. 

How to live more crunchy: 4 reasons to try it

Want some tips on how to start living a more crunchy, natural, holistic lifestyle, but not sure how to get started? Here are some ideas.

1. Embrace the Mind-Body Connection

  • Research is continuing to highlight how interconnected our mental and physical health are. From the gut-brain connection (13), to hypothalamic-pituitary-adrenal (HPA) axis (14), we are getting better at understanding how our thoughts and emotions can affect our physiological health. Bottom line is – it’s important to nurture our minds. Here are some ways to take care of your mental health, and correspondingly, your physical health:
    • Nurturing social connections and relationships. So go give your spouse or your kid a 20-second hug! (7)
    • Being involved in your community. Yeah, yeah, this means you need to say “hi” to your neighbors. (16)
    • Emotional self-care. Positive emotions can boost immune function! (13) So next time you’re under the weather, try watching some Dry Bar Comedy while you’re resting on the couch. 

2. Take a Whole-Person Approach to Health and Wellness

  • According to the National Center for Complementary and Integrative Health, “whole-person health” takes a holistic, multi-factor approach to health and wellness., rather than just focusing on symptoms  “Instead of treating a specific disease, whole person health focuses on restoring health, promoting resilience, and preventing diseases.” (8) This includes all sorts of healthy lifestyle changes, such as:
    • Eating enough nourishing food. Consuming too few calories is a well-known stressor on your body, just as harmful as too many! (15)
    • Regular movement and activity. 
    • Getting adequate sleep every night. Your circadian rhythm affects WAY more than just sleep and waking up! It influences digestion and metabolism, cognitive abilities, stress hormones…the list goes on. (17) So, let’s just all stop scrolling before bed, k?
    • Nurturing healthy relationships! (Remember how I mentioned this earlier? (7))

3. Use Preventative over Reactive Care

  • Chronic diseases have become the leading causes of death and disability worldwide. (9) While many of these diseases are not necessarily curable, they are preventable! Through healthy, proactive lifestyle choices, such as healthy eating, regular exercise, and avoiding tobacco and alcohol, many chronic diseases can be avoided or lessened. (9) 
  • In addition, complementary and alternative medicine choices are becoming more accessible and more supported by research. For example, these are all modalities that are being offered by more and more primary care providers (9):
    • Acupuncture
    • Biofeedback
    • Massage therapy
    • Yoga
    • Meditation 

4. Nurture Yourself with Nature

  • Getting out in nature and living more sustainably has a positive impact on our health. For example, it can encourage more movement, reduce stress and improve mood, help develop emotional resilience, and encourage mindful and ethical living. By and large, incorporating nature into our lives and making sustainable choices contribute to a holistic and balanced approach to well-being.
    • Get outside and get moving! You don’t need me to tell you about the benefits of physical activity (less anxiety, improved heart health, increased muscle mass and higher metabolic rate, reduced risk of osteoporosis…okay, I guess I told you after all(10).) So just go take a walk outside already, would ya?
    • Immersion in nature helps reduce stress and improve mood. (10) Go stand outside and stare at a tree and tell me you aren’t less stressed! I’ll wait.
    • Time in nature helps develop your emotional resilience. (11) 
    • Being outdoors helps encourage mindful and ethical living, which not only benefits your health, but our lovely little rock we call home as well. Win-win! (12)

If you want to live a little more crunchy but you don’t know where to start, follow along! Sign up for the Granola Science email list for monthly inspiration and tips that are crunchy AND science-based. Meanwhile, explore the blog for nourishing recipes and science-backed healthy living tips – you’ll be fermenting something on your kitchen counter in no time.

What else would you add to this list? How do you live a little more crunchy?
A woman sitting on a bed, stretching her arms overhead
References part 1:
  1. Calder P.C. et al. (2018) A holistic approach to healthy ageing: how can people live longer, healthier lives? J Hum Nutr Diet. 31, 439–450 https://doi.org/10.1111/jhn.12566
  2. Upchurch, D.M., Rainisch, B.W. The importance of wellness among users of complementary and alternative medicine: findings from the 2007 National Health Interview Survey. BMC Complement Altern Med 15, 362 (2015). https://doi.org/10.1186/s12906-015-0886-y
  3. Canales-Ronda, P. et al.. Healthy Lifestyle and Complementary and Alternative Medicine. Holistic Nursing Practice ():, August 06, 2021. | DOI: 10.1097/HNP.0000000000000476
  4. Casner, M. #Crunchy: The Construction of Scientific and Medical Expertise and Knowledge in the Crunchy Community on TikTok. August 2023. https://knowledge.uchicago.edu/record/7217.
  5. Dooley, E. Survey: People Turned to Gardening for Stress Relief, Food Access During Pandemic. March 2022. https://www.ucdavis.edu/food/news/survey-people-turned-gardening-stress-relief-food-access-during-pandemic 
  6. Mae, K.  Living A ‘Crunchy’ Lifestyle Is A Privilege. April 2019. https://www.scarymommy.com/privilege-crunchy-lifestyle 
  7. Alloway, T. What 20 Seconds of Hugging Can Do for You. January 2022. https://www.psychologytoday.com/us/blog/keep-it-in-mind/202201/what-20-seconds-hugging-can-do-you
  8. National Center for Complementary and Integrative Health (NCCIH). Whole Person Health: What You Need To Know. May 2021. https://www.nccih.nih.gov/health/whole-person-health-what-you-need-to-know
  9. Lee, A. Health-promoting schools. Appl Health Econ Health Policy 7, 11–17 (2009). https://doi.org/10.1007/BF03256138
References part 2:

10. Lawton, E. et al. The Relationship between the Physical Activity Environment, Nature Relatedness, Anxiety, and the Psychological Well-being Benefits of Regular Exercisers. June 2017. ​​https://doi.org/10.3389/fpsyg.2017.01058
11. Ernst, J. et al. The Nature and Nurture of Resilience: Exploring the Impact of Nature Preschools on Young Children’s Protective Factors. International Journal of Early Childhood Environmental Education, 2019. https://eric.ed.gov/?id=EJ1225648
12. Mayer, F. S., et al. Why Is Nature Beneficial?: The Role of Connectedness to Nature. Environment and Behavior. 2009. https://doi.org/10.1177/0013916508319745
13. Mayer, E. et al., The Gut–Brain Axis. Annual Review of Medicine. 2022. https://doi.org/10.1146/annurev-med-042320-014032
14. Smith SM, Vale WW. The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues Clin Neurosci. 2006;8(4):383-95. doi: 10.31887/DCNS.2006.8.4/ssmith. PMID: 17290797; PMCID: PMC3181830.
15. Seematter G. et al., Metabolic Effects of Mental Stress during Over- and Underfeeding in Healthy Women. Obesity Research. 2012. https://doi.org/10.1038/oby.2002.7
16. Wallerstein, Nina, et al. “Improving health through community engagement, community organization, and community building.” Health behavior: theory, research and practice 5 (2015).
17. Frazier, Katya, and Eugene B. Chang. “Intersection of the gut microbiome and circadian rhythms in metabolism.” Trends in Endocrinology & Metabolism 31.1 (2020): 25-36. DOI:https://doi.org/10.1016/j.tem.2019.08.013

Granola Science Posts referenced:
  1. Health benefits of practicing gratitude
  2. Stress

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Does Bile Help with Detoxification? Your Body’s Unsung Detox Hero https://rvy.ayu.mybluehost.me/bile-and-detoxification-pathways/?utm_source=rss&utm_medium=rss&utm_campaign=bile-and-detoxification-pathways https://rvy.ayu.mybluehost.me/bile-and-detoxification-pathways/#respond Sat, 05 Mar 2022 00:06:32 +0000 https://startertemplatecloud.com/g50/?p=274 Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Non arcu risus quis varius. Elit at imperdiet dui accumsan sit. Elit scelerisque mauris pellentesque pulvinar pellentesque habitant morbi tristique. Nibh ipsum consequat nisl vel pretium lectus. Lectus proin nibh nisl condimentum id venenatis. Elementum pulvinar...

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